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Categories: Biology: Biotechnology, Space: Astrophysics
Published Genetically modifying individual cells in animals
(via sciencedaily.com) Original source Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
Published Tag team of the James Webb Space Telescope and ALMA captures the core of the most distant galaxy protocluster
(via sciencedaily.com) An international research team has used the James Webb Space Telescope and the Atacama Large Millimeter/submillimeter Array to observe the most distant galaxy protocluster to date, 13.14 billion light-years away. The team has successfully captured the 'core region' of the galaxy protocluster, which corresponds to a metropolitan area with a particularly high number density of galaxies. The team has revealed that many galaxies are concentrated in a small area and that the growth of galaxies is accelerated. Furthermore, the team used simulations to predict the future of the metropolitan area and found that the region will merge into one larger galaxy within tens of millions of years. These results are expected to provide important clues regarding the birth and growth of galaxies.
Published Sometimes beneficial, sometimes damaging: The double role of the enzyme chameau
(via sciencedaily.com) Original source Biologists have discovered why an enzyme is important for the survival of fruit flies, even though it can shorten their lives under certain conditions.
Published Spider silk is spun by silkworms for the first time, offering a green alternative to synthetic fibers
(via sciencedaily.com) Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.
Published Black holes eat faster than previously expected
(via sciencedaily.com) While previous researchers have hypothesized that black holes eat slowly, new simulations indicate that black holes scarf food much faster than conventional understanding suggests. Some quasars brighten and disappear within months -- a time scale that aligns with the new findings.
Published Fast-track strain engineering for speedy biomanufacturing
(via sciencedaily.com) Using engineered microbes as microscopic factories has given the world steady sources of life-saving drugs, revolutionized the food industry, and allowed us to make sustainable versions of valuable chemicals previously made from petroleum. But behind each biomanufactured product on the market today is the investment of years of work and many millions of dollars in research and development funding. Scientists want to help the burgeoning industry reach new heights by accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.
Published Tiny sea creatures reveal the ancient origins of neurons
(via sciencedaily.com) Original source A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.
Published RNA for the first time recovered from an extinct species
(via sciencedaily.com) Original source A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the woolly mammoth, as well as for studying pandemic RNA viruses.
Published Tracking down the formation of cardenolides in plants
(via sciencedaily.com) Original source Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.
Published Groundbreaking research shows that the limits of nuclear stability change in stellar environments where temperatures reach billions of degrees Celsius
(via sciencedaily.com) Original source New research is challenging the scientific status quo on the limits of the nuclear chart in hot stellar environments where temperatures reach billions of degrees Celsius.
Published Brilliant galaxies of early universe
(via sciencedaily.com) Scientists have used data from the James Webb Space Telescope (JWST) as part of the Cosmic Evolution Early Release Science (CEERS) Survey to change the way we think about the universe and its distant galaxies. Astronomers authored a paper confirming very bright galaxies in the early universe, while also disproving the identification of what would have been the most distant galaxy ever found.
Published Genome editing: Reducing off-target mutations in DNA
(via sciencedaily.com) Original source Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.
Published Snaps supersonic outflow of young star
(via sciencedaily.com) Herbig-Haro (HH) objects are luminous regions surrounding newborn stars, formed when stellar winds or jets of gas spewing from these newborn stars form shock waves colliding with nearby gas and dust at high speeds. This image of HH 211 from NASA's James Webb Space Telescope reveals an outflow from a Class 0 protostar, an infantile analog of our Sun when it was no more than a few tens of thousands of years old and with a mass only 8% of the present-day Sun (it will eventually grow into a star like the Sun).
Published Genetically modified bacteria break down plastics in saltwater
(via sciencedaily.com) Original source Researchers have genetically engineered a marine microorganism to break down plastic in salt water. Specifically, the modified organism can break down polyethylene terephthalate (PET), a plastic used in everything from water bottles to clothing that is a significant contributor to microplastic pollution in oceans.
Published Specialized gut immune cells pinpointed that can limit progression of inflammatory bowel disease
(via sciencedaily.com) Original source Researchers have characterized a specialized type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.
Published Researchers discover tissue-specific protection against protein aggregation
(via sciencedaily.com) Original source Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protein build up, this research could accelerate the identification of ways to protect tissues that are vulnerable to protein build up, possibly tackling both disease-associated protein aggregates and also age-dependent aggregates that accelerate the functional decline of tissues.
Published Carbon atoms coming together in space
(via sciencedaily.com) Original source Lab-based studies reveal how carbon atoms diffuse on the surface of interstellar ice grains to form complex organic compounds, crucial to reveal the chemical complexity in the universe.
Published Electrons from Earth may be forming water on the Moon
(via sciencedaily.com) Planetary scientists have discovered that high energy electrons in Earth's plasma sheet are contributing to weathering processes on the Moon's surface and, importantly, the electrons may have aided the formation of water on the lunar surface.
Published Mysterious family of microbial proteins hijack crops' cellular plumbing
(via sciencedaily.com) Original source Some crop pathogens use a clever trick to multiply and spread infection: they hijack the plant's cellular plumbing. In a new study, researchers unveil a class of bacterial proteins that fold into a straw-like shape and insert themselves into the plant cell membrane, allowing the inside of the leaf to become waterlogged. The researchers also figured out a possible way to block the water channel proteins and prevent infection.
Published Natural compound found in plants inhibits deadly fungi
(via sciencedaily.com) Original source A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi -- including its most virulent species, Candida auris, an emerging global health threat.