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Categories: Biology: Biotechnology, Mathematics: Statistics
Published Genetic atlas detailing early stages of zebrafish development
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Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.
Published Acid sensor and calcium store discovered in plants
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Using optogenetics, researchers have detected a new acid sensor in plant cells that is addressing a cell-internal calcium store.
Published Ancient DNA reveals how a chicken virus evolved to become more deadly
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An international team of scientists led by geneticists and disease biologists has used ancient DNA to trace the evolution of Marek's Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year. The findings show how viruses evolve to become more virulent and could lead to the development of better ways to treat viral infections.
Published Can you change a chicken into a frog, a fish or a chameleon?
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Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.
Published How the immune system fights to keep herpes at bay
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In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published New understanding of ancient genetic parasite may spur medical breakthroughs
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Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
Published Enzymes can't tell artificial DNA from the real thing
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Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Earliest evidence for domestic yak found using both archaeology, ancient DNA
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The high-altitude hero of the Himalayas, yak are among the few large animals that can survive the extremely cold, harsh and oxygen-poor conditions of the Tibetan Plateau. In the mountainous regions of Asia, yak and yak-cattle hybrids serve as vital sources of meat, milk, transportation and fuel. However, little is known about their history: when or where yak were domesticated. In a new study, researchers report archaeologically and genetically confirmed evidence for domestic yak, dating back 2,500 years, by far the oldest record.
Published Scientists unveil complete cell map of a whole mammalian brain
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Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Nanoprobe with a barcode
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Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.
Published Cells move in groups differently than they do when alone
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A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published Mice possess natural gene therapy system
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A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published A rare enzyme role change with bacterial defense system assembly
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Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published A new mechanism by which rotavirus makes you sick
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Scientists report a new mechanism by which rotavirus induces diarrhea by interfering with the normal absorption of nutrients in the intestine.
Published Zika's shape-shifting machinery, and a possible vulnerability
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Viruses have limited genetic material -- and few proteins -- so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now researchers have shown how the virus does so much with so little and may have identified a therapeutic vulnerability.
Published How immune cells recognize their enemies
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In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams a have identified new details in this process.
Published New genes can arise from nothing
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The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.
Published Fungus-fighting protein could help overcome severe autoimmune disease and cancer
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A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research has found. The discovery could pave the way for new and more effective drugs, without the nasty side effects of existing treatments. In addition to helping to manage severe autoimmune conditions, the breakthrough could also help treat all types of cancer.
Published Influx of water and salts propel immune cells through the body
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Researchers have shown that an influx of water and ions into immune cells allows them to migrate to where they're needed in the body.
Published From infamy to ingenuity: Bacterial hijack mechanisms as advanced genetic tools
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Researchers have uncovered the intricate molecular mechanism used by parasitic phytoplasma bacteria, known for inducing 'zombie-like' effects in plants.