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Categories: Biology: Biotechnology, Space: Astronomy

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A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.

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Black soldier flies are now commercially used to consume organic waste -- but genetic modifications proposed by bioscientists could see the insects digesting a wider variety of refuse, while also creating raw ingredients for industry.

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Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.

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A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.

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With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.

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The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and cancer. Macrophages have a delicate task. It's crucial that they ignore healthy cells while on patrol, otherwise they could trigger an autoimmune response while performing their duties.

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Researchers genetically modified poplar trees to produce high-performance, structural wood without the use of chemicals or energy intensive processing.

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A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.

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A new, two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs, researchers report.

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While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.

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Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.

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A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

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A new artificial intelligence model can predict how different proteins may bind to DNA.

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The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.

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An interdisciplinary team of medical and engineering researchers has spent the last six years working to unlock a significant piece of the puzzle in the search for a cure: how and where the gluten response begins.

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Researchers develop a microstructured 'artificial lung' model using bioprinting technology.

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Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

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There comes a point in the lives of young owl monkeys when they leave their parents and strike out on their own to find a mate. In a new study of a wild population of Azara's owl monkeys in northern Argentina, researchers reveal that a combination of social and ecological factors influences when these tree-dwelling monkeys peel away from their parents and siblings. According to their findings -- which were based on 25 years of genetic and demographic data for several generations of owl monkeys, covering more than 330 individuals -- none of the individuals, regardless of their sex, reproduced in the same group where they were born. In all cases, the researchers found, the animals either departed from their natal group or died before reproducing.

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Scientists discovered a role played by ribosomes during the folding of new proteins in cells.

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A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.