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Categories: Biology: Biotechnology, Space: Astronomy
Published Elucidating the mysteries of enzyme evolution at the macromolecular level
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Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, including the development of new drugs to treat serious diseases such as cancer or to counter antibiotic resistance.
Published Scientist uncovers roots of antibiotic resistance
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Microbiologists have uncovered the evolutionary origins of antimicrobial resistance (AMR) in bacteria. His studies on the bacterium that causes cholera, Vibrio cholerae, provide insight into deciphering what conditions must occur for infectious agents to become resistant. He studied genetic variants of a protein found in bacterial membranes called OmpU. Using computational and molecular approaches, his team found that several OmpU mutations in the cholera bacteria led to resistance to numerous antimicrobial agents. This resistance included antimicrobial peptides that act as defenses in the human gut.
Published Gutless marine worms on a Mediterranean diet: Animals can synthesize phytosterols
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Phytosterols are good for your health, but humans and other animals are not able to make them themselves, only plants can. To acquire phytosterols, humans are increasingly turning to supplements, green smoothies, or a Mediterranean diet with plenty of plant-based foods. Researchers have now discovered that tiny gutless worms from the Mediterranean can synthesize phytosterols on their own. Their study provides evidence that many other animals also have the genes needed to make their own phytosterols.
Published Alternative 'fuel' for string-shaped motors in cells
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Researchers discover a unique two-component molecular motor that uses a kind of renewable chemical energy to pull vesicles toward membrane-bound organelles.
Published Hubble follows shadow play around planet-forming disk
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The young star TW Hydrae is playing 'shadow puppets' with scientists observing it with NASA's Hubble Space Telescope. In 2017, astronomers reported discovering a shadow sweeping across the face of a vast pancake-shaped gas-and-dust disk surrounding the red dwarf star. The shadow isn't from a planet, but from an inner disk slightly inclined relative to the much larger outer disk -- causing it to cast a shadow. One explanation is that an unseen planet's gravity is pulling dust and gas into the planet's inclined orbit. The young star TW Hydrae is playing 'shadow puppets' with scientists observing it with NASA's Hubble Space Telescope. Now, a second shadow -- playing a game of peek-a-boo -- has emerged in just a few years between observations stored in Hubble's MAST archive. This could be from yet another disk nestled inside the system. The two disks are likely evidence of a pair of planets under construction.
Published Astronomers spot a star swallowing a planet
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Scientists have observed a star swallowing a planet for the first time. Earth will meet a similar fate in 5 billion years.
Published Scientists recover an ancient woman's DNA from a 20,000-year-old pendant
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An international research team has for the first time successfully isolated ancient human DNA from a Paleolithic artefact: a pierced deer tooth discovered in Denisova Cave in southern Siberia. To preserve the integrity of the artefact, they developed a new, nondestructive method for isolating DNA from ancient bones and teeth. From the DNA retrieved they were able to reconstruct a precise genetic profile of the woman who used or wore the pendant, as well as of the deer from which the tooth was taken. Genetic dates obtained for the DNA from both the woman and the deer show that the pendant was made between 19,000 and 25,000 years ago. The tooth remains fully intact after analysis, providing testimony to a new era in ancient DNA research, in which it may become possible to directly identify the users of ornaments and tools produced in the deep past.
Published Astronomers find distant gas clouds with leftovers of the first stars
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Using ESO's Very Large Telescope (VLT), researchers have found for the first time the fingerprints left by the explosion of the first stars in the Universe. They detected three distant gas clouds whose chemical composition matches what we expect from the first stellar explosions. These findings bring us one step closer to understanding the nature of the first stars that formed after the Big Bang.
Published A novel stem cell adhesive using mussels
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A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid.
Published Chances of eliminating HIV infection increased by novel dual gene-editing approach
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Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research shows. The study combines a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts
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Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Wiggly proteins guard the genome
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Dynamic network in the pores of the nuclear envelope blocks dangerous invaders.
Published Webb finds water vapor, but from a rocky planet or its star?
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Astronomers used NASA's James Webb Space Telescope to study a rocky exoplanet known as GJ 486 b. It is too close to its star to be within the habitable zone, with a surface temperature of about 800 degrees Fahrenheit (430 degrees Celsius). And yet, their observations show hints of water vapor.
Published Herpes study adds to understanding of viral reinfections, how to potentially prevent them
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A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.
Published Astronomers detect 'nearby' black hole devouring a star
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Astronomers have discovered a new 'tidal disruption event,' in which the center of a galaxy lights up as its supermassive black hole rips apart a passing star. The outburst is the closest tidal disruption event observed to date, and one of the first to be identified at infrared wavelengths.
Published Scientists identify antivirals that could combat emerging infectious diseases
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A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
Published Superflare with massive, high-velocity prominence eruption
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A team of Japanese astronomers used simultaneous ground-based and space-based observations to capture a more complete picture of a superflare on a star. The observed flare started with a very massive, high-velocity prominence eruption. These results give us a better idea of how superflares and stellar prominence eruptions occur.
Published Scientists slow aging by engineering longevity in cells
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Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
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CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
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What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.