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Categories: Biology: Biotechnology, Physics: General

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The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.

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A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

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To overcome global energy challenges and fight the looming environmental crisis, researchers around the world investigate new materials for converting sunlight into electricity. Some of the most promising candidates for high-efficiency low-cost solar cell applications are based on lead halide perovskite (LHP) semiconductors. Despite record-breaking solar cell prototypes, the microscopic origin of the surprisingly excellent optoelectronic performance of this material class is still not completely understood. Now, an international team of physicists and chemists has demonstrated laser-driven control of fundamental motions of the LHP atomic lattice.

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Ultrafast laser physicists from the attoworld team have gained new insights into the dynamics of electrons in solids immediately after photoinjection.

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Nuclear clocks could allow scientists to probe the fundamental forces of the universe in the future. Researchers have made a crucial advance in this area as part of an international collaboration.

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Scientists have developed a nanodevice that can measure the absolute power of microwave radiation down to the femtowatt level at ultra-low temperatures -- a scale trillion times lower than routinely used in verifiable power measurements. The device has the potential to significantly advance microwave measurements in quantum technology.

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A hormone and specialized brain cells regulate feeding behavior in mice.

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Scientists have found a new way to create a crystalline structure called a 'density wave' in an atomic gas. The findings can help us better understand the behavior of quantum matter, one of the most complex problems in physics.

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Scientists have uncovered new clues about the origin of paired appendages -- a major evolutionary step that remains unresolved and highly debated.

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Researchers reveal how a nanomachine takes care of cleaning up inside the cell.

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Researchers have engineered bacteria to synthesize an amino acid that contains a rare functional group that others have shown to have implications in the regulation of our immune system. The researchers also taught a single bacterial strain to create the amino acid and place it at specific sites within target proteins. These findings provide a foundation for developing unique vaccines and immunotherapies in the future.

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Researchers have uncovered the atomic mechanisms that make a class of compounds called argyrodites attractive candidates for both solid-state battery electrolytes and thermoelectric energy converters. The discoveries -- and the machine learning approach used to make them -- could help usher in a new era of energy storage for applications such as household battery walls and fast-charging electric vehicles.

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A team of researchers has found a mechanism in thale cress (Arabidopsis thaliana) which enables plants to provide protection against salt stress for their sensitive stem cells in the meristem at the root tip.

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Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study that could help get to the bottom of why limiting sugary foods can ease symptoms for patients with IBD.

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Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.

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Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications.

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Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers have now been able to elucidate the exact mechanism at the atomic level.

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Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests. One of the greatest challenges in modern plant research is to identify the differences in genetic information that are responsible for this variation.

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Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.

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A University of Minnesota Twin Cities-led team has developed a first-of-its-kind breakthrough method that makes it easier to create high-quality metal oxide films that are important for various next generation applications such as quantum computing and microelectronics.