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Categories: Biology: Biotechnology, Engineering: Biometric
Published A miniature heart in a petri dish: Organoid emulates development of the human heart
(via sciencedaily.com) Original source A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.
Published Study to decode microbe-gut signaling suggests potential new treatment for IBD
(via sciencedaily.com) Original source Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Published Can investigators use household dust as a forensic tool?
(via sciencedaily.com) Original source It is possible to retrieve forensically relevant information from human DNA in household dust.
Published New research shows that bacteria get 'hangry,' too
(via sciencedaily.com) Original source Researchers have discovered, using a recently developed technology, that genetically identical cells within a bacterial community have different functions, with some members behaving more docile and others producing the very toxins that make us feel ill.
Published DELLA proteins could hold key to the next Green Revolution
(via sciencedaily.com) Original source A family of 'promiscuous' proteins found in all land plants is responsible for many different plant functions, despite remaining relatively unchanged for over 450 million years.
Published Cold is beneficial for healthy aging, at least in animals
(via sciencedaily.com) Original source A lower body temperature is one of the most effective mechanisms to prolong the lifespan of animals. New research has now described precisely how this works. The scientists show that cold can prevent the pathological aggregation of proteins typical for two aging-associated neurodegenerative diseases.
Published Wastewater more potent breeding ground for antibiotic resistance than previously known
(via sciencedaily.com) Wastewater is a more potent environment for antibiotic resistance to evolve than previously known. A study shows that wastewaters have unique characteristics, allowing resistance genes to start their journey from harmless bacteria to those that cause disease.
Published Engineered E. coli delivers therapeutic nanobodies to the gut
(via sciencedaily.com) Original source Researchers have succeeded in developing an E. coli-based 'smart microbe' that secretes therapeutic payloads, including antibodies, into the gut. The genetically modified beneficial strain of bacteria blocks intestinal inflammation in a preclinical model of inflammatory bowel disease and has the potential to treat intestinal-based diseases.
Published Microrobot technology: Externally connecting in vivo neural networks
(via sciencedaily.com) Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.
Published Form is (mal)function: Protein's shape lets bacteria disarm it
(via sciencedaily.com) Shigella bacteria can infect humans but not mice. A team can now explain why. Their findings may explain the multifariousness of a key weapon of our immune system.
Published Boosting the body's anti-viral immune response may eliminate aging cells
(via sciencedaily.com) Original source Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.
Published Scientists see anti-aging potential in an invasive weed
(via sciencedaily.com) Original source The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.
Published Scientists discover hidden crab diversity among coral reefs
(via sciencedaily.com) The Indo-West Pacific is the largest marine ecosystem on Earth, but scientists who study its diversity have to contend with a problem so well-known it was remarked upon by Charles Darwin: related species in the IWP have similar appearances, making it difficult to assess just how many there are. A new study reveals that nearly identical crab species have one consistently distinguishing feature, which only evolves when their ranges overlap.
Published Detecting coral biodiversity in seawater samples
(via sciencedaily.com) Researchers have developed a method to measure coral biodiversity through extracting the environmental DNA (or eDNA) from a liter of surface seawater collected from above a reef. The method has been confirmed to work through observations made by scientific divers in the same areas of ocean. This has paved the way for large-scale comprehensive surveys of reef-building coral to take place and removes the reliance of direct observations made through scientific scuba diving or snorkeling.
Published Marijuana-derived compounds could reverse opioid overdoses, researchers report
(via sciencedaily.com) Original source Naloxone -- a fast-acting opioid antidote -- has saved lives, but it's less effective against powerful synthetic opioids, such as fentanyl. In an interesting twist, researchers are now investigating cannabidiol (CBD), a component of marijuana, as a possible alternative to the popular antidote. Today, a team reports compounds based on CBD that reduce fentanyl binding and boost the effects of naloxone.
Published Components of cytoskeleton strengthen effect of sex hormones
(via sciencedaily.com) Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.
Published Epigenetic fingerprint as proof of origin for chicken, shrimp and salmon
(via sciencedaily.com) Free-range organic chicken or factory farming? Scientists have developed a new detection method that can reveal such differences in husbandry. The so-called epigenetic method is based on the analysis of the characteristic patterns of chemical markers on the genome of the animals.
Published What should we call evolution driven by genetic engineering? Genetic welding, says researcher
(via sciencedaily.com) With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations. An evolutionary geneticist proposes that we call this evolutionary meddling 'genetic welding.' He argues that we must scientifically and ethically scrutinize the potential consequences of genetic welding before we put it into practice.
Published Team designs molecule to disrupt SARS-CoV-2 infection
(via sciencedaily.com) A team of scientists designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
Published HIV genomes that hide in white blood cells offer new target to eliminate infections
(via sciencedaily.com) To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code. Now, in a study using blood samples from men and women with HIV on long-term suppressive therapy, a team of scientists reports new evidence that one such stable reservoir of HIV genomes can be found in circulating white blood cells called monocytes.