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Categories: Biology: Biotechnology, Engineering: Biometric
Published Study compares de novo proteins with randomly produced proteins
(via sciencedaily.com) Original source In a series of experiments, a team of researchers have compared de novo proteins with random-sequence proteins, looking at their stability and solubility. The results are set to advance basic research in this new field.
Published How skates learned to fly through water
(via sciencedaily.com) Original source Genes are not the only drivers of evolution. The iconic fins of skates are caused by changes in the non-coding genome and its three-dimensional structure, an international research team reports.
Published Oral barrier is similar in ceramide composition to skin barrier
(via sciencedaily.com) Original source Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.
Published Genes are read faster and more sloppily in old age
(via sciencedaily.com) Original source Scientists have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers. With dietary restrictions, these processes could be reversed.
Published British flower study reveals surprise about plants' sex life
(via sciencedaily.com) Original source A study of Britain's native flowering plants has led to new insights into the mysterious process that allows wild plants to breed across species -- one of plants' most powerful evolutionary forces. When wild flowering plants are sizing up others they may often end up in a marriage between close relatives rather than neighbors, a new study has revealed.
Published New approach targets norovirus, world's leading cause of foodborne infection
(via sciencedaily.com) Original source Researchers have found a creative way to make a vaccine for norovirus, the leading cause of foodborne infections, by piggybacking on rotavirus, an unrelated virus for which there are already several highly effective vaccines.
Published Stowaways in the genome
(via sciencedaily.com) Original source Scientists have discovered over 30,000 viruses by using the high-performance computer cluster 'Leo' and sophisticated detective work. The viruses hide in the DNA of unicellular organisms. In some cases, up to 10% of microbial DNA consists of built-in viruses.
Published Male yellow crazy ants are real-life chimeras
(via sciencedaily.com) Original source Researchers discovered that males of the yellow crazy ant have maternal and paternal genomes in different cells of their body and are thus chimeras.
Published A protective probiotic blunts the ill effects of alcohol in mice
(via sciencedaily.com) Original source A probiotic treatment reduced the negative effects of alcohol consumption in mice.
Published Engineered plants produce sex perfume to trick pests and replace pesticides
(via sciencedaily.com) Original source Tobacco plants have been engineered to manufacture an alluring perfume of insect sex pheromones, which could be used to confuse would-be pests looking for love and reduce the need for harmful pesticides.
Published Here's how a worm's embryonic cells changed its development potential
(via sciencedaily.com) Original source Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.
Published Woolly mammoths evolved smaller ears and woolier coats over the 700,000 years that they roamed the Siberian steppes
(via sciencedaily.com) Original source A team of researchers compared the genomes of woolly mammoths with modern day elephants to find out what made woolly mammoths unique, both as individuals and as a species. The investigators report that many of the woolly mammoth's trademark features -- including their woolly coats and large fat deposits -- were already genetically encoded in the earliest woolly mammoths, but these and other traits became more defined over the species' 700,000+ year existence. They also identified a gene with several mutations that may have been responsible for the woolly mammoth's miniscule ears.
Published Simple but revolutionary modular organoids
(via sciencedaily.com) Original source A team has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques. The group also recently demonstrated the ability to use the device to build organoids that faithfully reproduce the asymmetric genetic expression that characterizes the actual development of organisms.
Published Researchers clear the way for well-rounded view of cellular defects
(via sciencedaily.com) Original source New research investigates how cells divide, particularly in the fibrous environment of living tissue. Cells are typically studied in a flat environment, and the difference between flat and fibrous landscapes opens new windows into the behavior of cells and the diseases that impact them.
Published Broccoli consumption protects gut lining, reduces disease, in mice
(via sciencedaily.com) Original source Broccoli is known to be beneficial to our health. For example, research has shown that increased consumption of the cruciferous vegetable decreases incidence of cancer and type 2 diabetes. In a recent study, researchers found that broccoli contains certain molecules that bind to a receptor within mice and help to protect the lining of the small intestine, thereby inhibiting the development of disease. The findings lend support to the idea that broccoli truly is a 'superfood.'
Published Blind dating in bacteria evolution
(via sciencedaily.com) Original source A team of researchers reconstructed long-extinct proteins of a UV protection system of cyanobacteria. The surprising result: the proteins were already compatible with each other when they first met. This discovery expands the knowledge horizon on the rules of evolution.
Published Researchers create embryo-like structures from monkey embryonic stem cells
(via sciencedaily.com) Original source Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.
Published Activating adult-born neurons through deep brain stimulation alleviates Alzheimer's symptoms in rodent models
(via sciencedaily.com) Original source People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression. Investigators used mice to study a process through which new neurons are generated in adulthood, called adult hippocampus neurogenesis (AHN). The research showed that deep brain stimulation of new neurons helped restore both cognitive and noncognitive functions in mouse models of Alzheimer's disease.
Published Humans vs. Bacteria: Differences in ribosome decoding revealed
(via sciencedaily.com) Original source Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development.
Published Complex assembly process involved in DNA virus replication
(via sciencedaily.com) Original source In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral particle, or packaging of the viral genome?' Now, in a new study, scientists have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.