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Categories: Biology: Biotechnology, Energy: Alternative Fuels
Published Chances of eliminating HIV infection increased by novel dual gene-editing approach
(via sciencedaily.com) Original source Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research shows. The study combines a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts
(via sciencedaily.com) Original source Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Wiggly proteins guard the genome
(via sciencedaily.com) Original source Dynamic network in the pores of the nuclear envelope blocks dangerous invaders.
Published Herpes study adds to understanding of viral reinfections, how to potentially prevent them
(via sciencedaily.com) Original source A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.
Published Scientists identify antivirals that could combat emerging infectious diseases
(via sciencedaily.com) Original source A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
Published Scientists slow aging by engineering longevity in cells
(via sciencedaily.com) Original source Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
(via sciencedaily.com) Original source CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
(via sciencedaily.com) Original source What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease
(via sciencedaily.com) Original source Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published Maths unlocks molecular interactions that open window to how life evolved
(via sciencedaily.com) Original source Landmark research by mathematicians sets out the definitive picture of biological adaptation at the level of intermolecular interactions.
Published New findings indicate gene-edited rice might survive in Martian soil
(via sciencedaily.com) Original source New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published New chemistry can extract virgin-grade materials from wind turbine blades in one process
(via sciencedaily.com) Original source Researchers have developed a chemical process that can disassemble the epoxy composite of wind turbine blades and simultaneously extract intact glass fibers as well as one of the epoxy resin's original building blocks in a high quality. The recovered materials could potentially be used in the production of new blades.
Published Near-universal T cell immunity towards a broad range of bacteria
(via sciencedaily.com) Original source Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Ocean ecosystem: Mixotrophic microorganisms play key role
(via sciencedaily.com) Original source Researchers have identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters.
Published Luring the virus into a trap
(via sciencedaily.com) Original source Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Outstanding performance of organic solar cell using tin oxide
(via sciencedaily.com) Original source Organic solar cells have a photoactive layer that is made from polymers and small molecules. The cells are very thin, can be flexible, and are easy to make. However, the efficiency of these cells is still much below that of conventional silicon-based ones. Applied physicists have now fabricated an organic solar cell with an efficiency of over 17 percent, which is in the top range for this type of material. It has the advantage of using an unusual device structure that is produced using a scalable technique.
Published New biologic effective against major infection in early tests
(via sciencedaily.com) Original source A research team has shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus -- a bacterial species widely resistant to antibiotics.
Published It's not as difficult as you think to shout upwind
(via sciencedaily.com) Original source Why does it feel so difficult to shout upwind? The sensation is common enough to have found its way into an idiom about not being understood. Researchers wanted a scientific explanation for the phenomenon -- and there wasn't been one. They have now shown that our common sense understanding of this situation is wrong. It isn't harder to shout into the wind; it's just harder to hear yourself.
Published Transforming highways for high-speed travel and energy transport
(via sciencedaily.com) Original source Researchers developed a proof of concept for a superconducting highway that could transport vehicles and electricity, cooling the necessary superconductors with a pipeline of liquid hydrogen. Most magnetic levitation designs feature the superconductor inside the vehicle, which is suspended above a magnetic track. The authors decided to flip that arrangement upside down, putting the superconductor on the ground and giving each vehicle a magnet. The result is a system with multiple uses, placing it within the realm of affordability.