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Categories: Biology: Biochemistry, Chemistry: Biochemistry
Published Robotic nerve 'cuffs' could help treat a range of neurological conditions
(via sciencedaily.com) Original source Researchers have developed tiny, flexible devices that can wrap around individual nerve fibers without damaging them. The researchers combined flexible electronics and soft robotics techniques to develop the devices, which could be used for the diagnosis and treatment of a range of disorders, including epilepsy and chronic pain, or the control of prosthetic limbs.
Published Shoulder surgeons should rethink a common practice, study suggests
(via sciencedaily.com) Original source Many surgeons remove the bursa when repairing rotator cuff injuries, but a new animal study suggests that the small tissue helps with healing.
Published Barley plants fine-tune their root microbial communities through sugary secretions
(via sciencedaily.com) Original source Different types of barley recruit distinct communities of soil microbes to grow around their roots by releasing a custom mix of sugars and other compounds, according to a new study.
Published These jacks-of-all-trades are masters, too: Yeast study helps answer age-old biology question
(via sciencedaily.com) Original source The results suggest that internal -- not external -- factors are the primary drivers of variation in the types of carbon yeasts can eat, and the researchers found no evidence that metabolic versatility, or the ability to eat different foods, comes with any trade-offs. In other words, some yeasts are jacks-of-all-trades and masters of each.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Food in sight? The liver is ready!
(via sciencedaily.com) Original source What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Published Curiosity promotes biodiversity
(via sciencedaily.com) Original source Cichlid fishes exhibit differing degrees of curiosity. The cause for this lies in their genes, as reported by researchers. This trait influences the cichlids' ability to adapt to new habitats.
Published Herring arrives earlier in the Wadden Sea due to climate change
(via sciencedaily.com) Original source Due to the changing climate, young herring arrive in the Wadden Sea earlier and earlier in spring.
Published With hybrid brains, these mice smell like a rat
(via sciencedaily.com) Original source Mice lacking an olfactory system have had their sense of smell restored with neurons from rats, the first time scientists have successfully integrated the sensory apparatus of one species into another.
Published Estimating emissions potential of decommissioned gas wells from shale samples
(via sciencedaily.com) Original source Extracting natural gas from shale formations can provide an abundant, lower-carbon footprint fossil fuel, but also creates concerns over increased methane emissions. Researchers have now developed a new tool that can estimate the emission potential of shale wells after they are no longer active.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published Synthetic droplets cause a stir in the primordial soup
(via sciencedaily.com) Original source Our bodies are made up of trillions of different cells, each fulfilling their own unique function to keep us alive. How do cells move around inside these extremely complicated systems? How do they know where to go? And how did they get so complicated to begin with? Simple yet profound questions like these are at the heart of curiosity-driven basic research, which focuses on the fundamental principles of natural phenomena.
Published Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
(via sciencedaily.com) Original source Scientists have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a 'single cell protein' cultivated from microbes in soybean processing wastewater, paving the way for more sustainable fish farming practices.
Published 'Like a nanoscopic Moon lander': Scientists unlock secret of how pyramidal molecules move across surfaces
(via sciencedaily.com) Original source Scientists have watched a molecule move across a graphite surface in unprecedented detail. It turns out this particular molecule moves like a Moon lander -- and the insights hold potential for future nanotechnologies.
Published How do birds flock? Researchers do the math to reveal previously unknown aerodynamic phenomenon
(via sciencedaily.com) Original source How do birds fly in a coordinated and seemingly effortless fashion? Part of the answer lies in precise, and previously unknown, aerodynamic interactions, reports a team of mathematicians. Its breakthrough broadens our understanding of wildlife, including fish, who move in schools, and could have applications in transportation and energy.
Published Towards novel promising perovskite-type ferroelectric materials: High-pressure synthesis of rubidium niobate
(via sciencedaily.com) Original source Researchers have pioneered a breakthrough in ferroelectric material development. They've engineered a novel displacement-type ferroelectric material boasting remarkable dielectric properties. Their achievement includes the successful synthesis of rubidium niobate (RbNbO3), a compound previously deemed challenging to produce under pressures exceeding 40,000 atmospheres. Additionally, they characterized how polarization changes across a wide temperature range during phase transitions. This breakthrough can lead to new design guidelines for ferroelectric materials.
Published Advanced cell atlas opens new doors in biomedical research
(via sciencedaily.com) Original source Researchers have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about human health and disease.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published How immune cells communicate to fight viruses
(via sciencedaily.com) Original source Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers have now developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors.
Published Unveiling the lionfish invasion in the Mediterranean Sea
(via sciencedaily.com) Original source Researchers have published a comprehensive study on the invasion of lionfish in the Mediterranean Sea, highlighting a rapid spread and the potential ecological impacts. The research shows the lionfish species Pterois miles has significantly expanded its territory in the Mediterranean since the invasion began around ten years ago. The invasive species has established presence in the eastern Mediterranean, with observations now extending to colder waters previously thought to be unsuitable for the species.