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Categories: Biology: Biochemistry, Chemistry: Biochemistry
Published Putting sound waves to work to create safer public spaces



Absorbing excess sound to make public environments like theaters and concert halls safer for hearing and using the unwanted sound waves to create electricity is the aim of a new paper. The authors built a system of piezoelectric sensors that can be installed in walls, floors, and ceilings to absorb sound waves and collect their energy. They used computer simulations to fine-tune variables including the voltage needed to power the main device component, the frequency and intensity of the input sound, and piezoelectric sensors tested in parallel and serial configurations.
Published How tiny hinges bend the infection-spreading spikes of a coronavirus



Far from being stiff and pointy, a coronavirus's infectious spikes are shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on its slender stalk. A new study suggests that disabling those hinges could block infection.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork



Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published Hormonal contraceptives in teens may alter risk assessment, rat study suggests



Hormonal contraceptives taken by adolescents may influence development of the brain in a way that alters the recognition of risks, a new study in rats suggests.
Published This wireless, handheld, non-invasive device detects Alzheimer's and Parkinson's biomarkers



An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases. The biosensor can also transmit the results wirelessly to a laptop or smartphone. The team tested the device on in vitro samples from patients and showed that it is as accurate as the state of the art method. Ultimately, researchers plan to test saliva and urine samples with the biosensor. The device could be modified to detect biomarkers for other conditions as well. The device relies on electrical rather than chemical detection, which researchers say is easier to implement and more accurate.
Published Evolution of taste: Early sharks were able to perceive bitter substances



New genetic data show that humans and sharks share bitter taste receptors, even though their evolutionary pathways separated nearly 500 million years ago.
Published Ammonia fuel offers great benefits but demands careful action



Researchers have identified the potential environmental risks of using ammonia as a zero-carbon fuel in order to develop an engineering roadmap to a sustainable ammonia economy.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life



An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight



A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.
Published AI programs spat out known data and hardly learned specific chemical interactions when predicting drug potency



Artificial intelligence (AI) is on the rise. Until now, AI applications generally have 'black box' character: How AI arrives at its results remains hidden. A cheminformatics scientist has now developed a method that reveals how certain AI applications work in pharmaceutical research. The results are unexpected: the AI programs largely remembered known data and hardly learned specific chemical interactions when predicting drug potency.
Published Cycle of fasting and feeding is crucial for healthy aging



Fasting interventions, which involve alternating periods of fasting and refeeding, are generally thought to improve health. But these interventions don't work as well in old animals. The question is: Why? By studying the short-lived killifish, researchers have shown that older fish deviate from a youthful fasting and refeeding cycle, and instead enter a state of perpetual fasting, even when ingesting food. However, the benefits of refeeding after fasting in old killifish can be restored by genetically activating a specific subunit of AMP kinase, an important sensor of cellular energy. These mutant fish experienced improved health and longevity, indicating that both fasting and refeeding are needed to confer health benefits and act through AMP kinase to do so.
Published Recycling of water-based adhesive achieved by changing pH



A research team has developed a reversible, water-based glue that has good adhesion in the neutral pH range, but can be detached again in strongly acidic or alkaline environments. The novel adhesive system, which is based on electrostatic interactions, has bond strengths somewhere between those of structural adhesives and pressure-sensitive adhesives. The new adhesive also bonds 'difficult' surfaces such as water-repellent polypropylene.
Published Mysterious new moth species discovered in Europe



European Lepidoptera (butterflies and moths), with a currently known inventory of approximately 11,000 species, are generally considered well-researched. However, a new genus and species from the Geometrid moth family tell a different story. The moth, named Mirlatia arcuata, is one of the most remarkable discoveries in Lepidoptera of recent decades.
Published Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke



Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.
Published Forming ice: There's a fungal protein for that



New research explores how proteins produced by a common fungus trigger ice nucleation at warm temperatures. The study holds potential implications for improving our understanding of how life affects precipitation and climate.
Published New study indicates C4 crops less sensitive to ozone pollution than C3 crops



Researchers have studied the effects of elevated O3 on five C3 crops (chickpea, rice, snap bean, soybean, wheat) and four C4 crops (sorghum, maize, Miscanthus × giganteus, switchgrass). Their findings indicate that C4 crops are much more tolerant of high O3 concentrations than C3 crops.
Published The Goldilocks Effect: Researchers establish framework for protein regulation



Researchers are working to understand how protein quality control works in cells.
Published New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells



Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process. Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.
Published Yucatán's underwater caves host diverse microbial communities



With help from an experienced underwater cave-diving team, researchers have constructed the most complete map to date of the microbial communities living in the submerged labyrinths beneath Mexico's Yucatán Peninsula. Researchers found the cave system's microbiome is distinct from the nearby sea, and microbial communities vary between cave systems forming distinct 'neighborhoods.'
Published quantum mechanics: Unlocking the secrets of spin with high-harmonic probes



Deep within every piece of magnetic material, electrons dance to the invisible tune of quantum mechanics. Their spins, akin to tiny atomic tops, dictate the magnetic behavior of the material they inhabit. This microscopic ballet is the cornerstone of magnetic phenomena, and it's these spins that a team of researchers has learned to control with remarkable precision, potentially redefining the future of electronics and data storage.