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Categories: Biology: Biochemistry, Chemistry: Biochemistry
Published Five new species of soft-furred hedgehogs from Southeast Asia
(via sciencedaily.com) Original source A new study identifies five new species of soft-furred hedgehogs from Southeast Asia. The study used DNA analysis and physical characteristics to describe two entirely new species of soft-furred hedgehogs and elevate three subspecies to the level of species.
Published New tool unifies single-cell data
(via sciencedaily.com) Original source A new methodology that allows for the categorization and organization of single-cell data has been launched. It can be used to create a harmonized dataset for the study of human health and disease.
Published Location, location, location: The hidden power of intracellular neighborhoods
(via sciencedaily.com) Original source New findings provide details about the hidden organization of the cytoplasm, showing it makes a big difference where in that cellular broth that messenger RNA (mRNA) get translated into proteins. The findings hold promise for increasing or altering the production of proteins in mRNA vaccines and therapies.
Published Inside the matrix: Nanoscale patterns revealed within model research organism
(via sciencedaily.com) Original source Following years of research and the power of a technologically advanced instrument, scientists have detailed the complex nanoscale exoskeleton patterns of the roundworm, a model laboratory organism, revealing clues about how skin layers are bound together.
Published The future of canine stem cell therapy: unprecedented, painless, and feeder-free
(via sciencedaily.com) Original source Scientists have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.
Published The key mechanism to cell growth has been elucidated
(via sciencedaily.com) Original source Researchers have discovered how amino acids activate a key cell, TORC1, which is a master regulator in living organisms that controls whether cells grow or recycle their contents in yeast. Notably, the team found that the amino acid cysteine is sensed by a protein called Pib2 and that the two bind together to trigger TORC1. This is important because faulty TORC1 has been linked to disease such as cancer.
Published Insects already had a variety of defense strategies in the Cretaceous
(via sciencedaily.com) Original source Analyses of amber show that insect larvae were already using a wide variety of tactics to protect themselves from predators 100 million years ago.
Published Bugs that help bugs: How environmental microbes boost fruit fly reproduction
(via sciencedaily.com) Original source A research group found that in female fruit flies, microorganisms enhance reproductive function, boosting the number of cells that form eggs and the number of mature eggs. This is done by controlling the release of hormones to speed up cell division in the ovaries, and limiting programmed cell death. These findings could improve reproductive medicine and could aid the development of new methods to enhance fertility.
Published Researchers solve mystery behind DnaA protein's role in DNA replication initiation
(via sciencedaily.com) Original source Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.
Published New insights revealed on tissue-dependent roles of JAK signaling in inflammation
(via sciencedaily.com) Original source Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Published Are diamonds GaN's best friend? Revolutionizing transistor technology
(via sciencedaily.com) Original source A research team has fabricated a gallium nitride (GaN) transistor using diamond, which of all natural materials has the highest thermal conductivity on earth, as a substrate, and they succeeded in increasing heat dissipation by more than two times compared with conventional transistors. The transistor is expected to be useful not only in the fields of 5G communication base stations, weather radar, and satellite communications, but also in microwave heating and plasma processing.
Published Unconventional magnets: Stress reduces frustration
(via sciencedaily.com) Original source An international research team recently demonstrated how magnetism can be actively changed by pressure.
Published Could an electric nudge to the head help your doctor operate a surgical robot?
(via sciencedaily.com) Original source People who received gentle electric currents on the back of their heads learned to maneuver a robotic surgery tool in virtual reality and then in a real setting much more easily than people who didn't receive those nudges, a new study shows.
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper
(via sciencedaily.com) Original source A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published Discovery: Plants use 'Trojan horse' to fight mold invasions
(via sciencedaily.com) Original source Scientists have discovered that plants send tiny, innocuous-seeming lipid 'bubbles' filled with RNA across enemy lines, into the cells of the aggressive mold. Once inside, different types of RNA come out to suppress the infectious cells that sucked them in.
Published Shedding light on the microbiome and kidney stones
(via sciencedaily.com) Original source A new study has found changes in the microbiome in multiple locations in the body are linked to the formation of kidney stones.
Published New larks revealed in Africa
(via sciencedaily.com) Original source Researchers have studied the relationships between five closely related species of larks that occur in Africa south of the Sahara. Two of these have not been observed for decades, so the researchers analyzed DNA from museum specimens, some of which were over 100 years old.
Published Common insect species are suffering the biggest losses
(via sciencedaily.com) Original source Insect decline is being driven by losses among the locally more common species, according to a new study. The meta-analysis of 923 locations around the world notes two significant trends: 1) the species with the most individuals (the highest abundance) are disproportionately decreasing in number, and 2) no other species have increased to the high numbers previously seen. This likely explains the frequent observation that there are fewer insects around now than ten, twenty, or thirty years ago.
Published A trillion scents, one nose
(via sciencedaily.com) Original source A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities
(via sciencedaily.com) Original source The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.