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Categories: Biology: Biochemistry, Paleontology: Fossils

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Hormonal contraceptives taken by adolescents may influence development of the brain in a way that alters the recognition of risks, a new study in rats suggests.

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New genetic data show that humans and sharks share bitter taste receptors, even though their evolutionary pathways separated nearly 500 million years ago.

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An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division. 

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A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.

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Fasting interventions, which involve alternating periods of fasting and refeeding, are generally thought to improve health. But these interventions don't work as well in old animals. The question is: Why? By studying the short-lived killifish, researchers have shown that older fish deviate from a youthful fasting and refeeding cycle, and instead enter a state of perpetual fasting, even when ingesting food. However, the benefits of refeeding after fasting in old killifish can be restored by genetically activating a specific subunit of AMP kinase, an important sensor of cellular energy. These mutant fish experienced improved health and longevity, indicating that both fasting and refeeding are needed to confer health benefits and act through AMP kinase to do so.

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European Lepidoptera (butterflies and moths), with a currently known inventory of approximately 11,000 species, are generally considered well-researched. However, a new genus and species from the Geometrid moth family tell a different story. The moth, named Mirlatia arcuata, is one of the most remarkable discoveries in Lepidoptera of recent decades.

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Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.

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New research explores how proteins produced by a common fungus trigger ice nucleation at warm temperatures. The study holds potential implications for improving our understanding of how life affects precipitation and climate.

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Researchers have studied the effects of elevated O3 on five C3 crops (chickpea, rice, snap bean, soybean, wheat) and four C4 crops (sorghum, maize, Miscanthus × giganteus, switchgrass). Their findings indicate that C4 crops are much more tolerant of high O3 concentrations than C3 crops.

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Researchers are working to understand how protein quality control works in cells. 

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Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.  Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.

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With help from an experienced underwater cave-diving team, researchers have constructed the most complete map to date of the microbial communities living in the submerged labyrinths beneath Mexico's Yucatán Peninsula. Researchers found the cave system's microbiome is distinct from the nearby sea, and microbial communities vary between cave systems forming distinct 'neighborhoods.'  

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Biologists have discovered a phosphorus-based bacterial metabolism that is both new and ancient. In a special role: a calculation from the 1980s, a sewage plant, a new bacterial organism, and a remnant from around 2.5 billion years ago.    

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An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

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Hummingbirds are highly maneuverable fliers, flitting forward and backward as they home in on flowers. But in the dense foliage many inhabit, they often encounter gaps that are too narrow for their wingspan. Since they can't bend their wings in flight, how do they get through? Researchers used high-speed cameras to capture their movements, discovering two unique strategies: they sidle through while fluttering, or fold their wings in a tuck and glide.

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An analysis of beeswax in managed honeybee hives in New York finds a wide variety of pesticide, herbicide and fungicide residues, exposing current and future generations of bees to long-term toxicity.

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A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.

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Researchers have developed a new way of counting microorganisms that works as much as 36 times faster than conventional methods, cuts plastic use more than 15-fold and substantially decreases the cost and carbon footprint of biomedical research. The technique could revolutionize the way microbiology experiments are conducted, allowing researchers to test potential new antibiotics in a fraction of the time.

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Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

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Rather than a slow, gradual process as Darwin envisioned, biologists can now see how evolutionary changes unfold on much more accelerated timescales. Using an accelerated arms race between bacteria and viruses, researchers are documenting rapid evolutionary processes in simple laboratory flasks in only three weeks.