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Categories: Biology: Biochemistry, Paleontology: Fossils

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New research has revealed a previously unknown process through which pathogens are able to defeat a cell's defense mechanisms with physical force. The discovery represents a potential game-changer in the fight against intracellular pathogens, which cause infectious diseases such as tuberculosis, malaria and chlamydia.

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Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded species such as mammals are produced in secondary lymphoid microstructures (SLMs) among which germinal centers (GCs) are the centerpiece. Despite the apparent absence of GCs or similar SLMs in cold-blooded vertebrates (e.g., fish), these species can mount significant antibody responses that can persist for several months. Thus, for decades, the outstanding question has remained as to how and where antibody responses are generated in species that lack GCs or analogous SLM structures.

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Some nonnative plants cultivated in public gardens or arboretums are escaping to become invasive in wild forests.

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Children must be taught more about the importance of plants if education about climate change and sustainability is to be effective, experts have warned.

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A simple-to-apply, needle-free vaccine patch is being developed to protect people from the potentially deadly mosquito-borne Zika virus.

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Pentoses are essential carbohydrates in the metabolism of modern lifeforms, but their availability on early Earth is unclear since these molecules are unstable. Now, researchers reveal a chemical pathway compatible with early Earth conditions, by which C6 aldonates could have acted as a source of pentoses without the need for enzymes. Their findings provide clues about primitive biochemistry and bring us closer to understanding life's origin.

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Maternal-fetal listeriosis is a severe disease that can lead to miscarriage, premature birth or serious neonatal infection. But what are the long-term consequences of neonatal listeriosis on the health of surviving infants? A team of scientists and physicians monitored the development of children infected with the bacterium Listeria monocytogenes up to the age of 5, and compared their development with that of uninfected gestational age-matched children. The study showed that the long-term outcomes of neonatal listeriosis were mainly due to prematurity.

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For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.

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During a two-year survey of soft corals in the Florida Keys,  scientists identified three species of octocorals that have survived heat waves. While the coral animal itself may be heat tolerant, scientists concluded that the symbiotic algae inside the coral serve as a protector of sorts.

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Scientists sequenced the genome of the East Asian pitcher plant, Nepenthes gracilis, a species of carnivorous plant related to Venus flytraps, as well as sundews, beets and spinach.

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In sea fireflies' underwater ballet, the males sway together in perfect, illuminated synchronization, basking in the glow of their secreted iridescent mucus.

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As California, the U.S. and the world work to make good on commitments to conserve 30% of oceans and lands by 2030, all strategies are on the table -- and under the microscope. When it comes to the ocean, one valuable tool is marine protected areas (MPAs), regions that are defined, designated and managed for long-term conservation. Among other benefits, MPAs protect habitats and promote species diversity. They also hold value for communities and industries.  

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Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.

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The increased legalization of cannabis over the past several years can potentially increase its co-use with alcohol. Concerningly, very few studies have looked at the effects of these two drugs when used in combination. In a series of new studies, researchers at used rats to understand how brain structure and behavior can change when cannabis and alcohol are taken together.

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There's a species of ant that is so rare, only a handful of records exist from across the entire eastern United States. North Carolina State University researcher Michelle Kirchner not only found these ants in the Triangle region of North Carolina, she is the first to document an entire colony for scientists, taxonomists and ant-thusiasts everywhere. It is the first time males of the species have been collected or photographed.

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Researchers have discovered that the waxy protective barrier around plants might play a role in sending chemical signals to other plants and insects.  

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Playing an essential foundational role in an ecosystem, plants contribute to the well-being of human health by helping create resources like food and medicine. Therefore, to better understand how plants can maintain resiliency in the face of challenges like climate change, researchers recently developed an innovative mathematical model that can provide fast and reliable predictions of how far wind can carry a plant's seeds.

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Plastic waste in the water might be stopping -- or interrupting -- some shrimp-like creatures from reproducing. In a unique study, the ability of 'shrimp like' creatures to reproduce successfully was found to be compromised by chemicals found in everyday plastics.    

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Scientists should seek answers hidden in the dirt using proven and state-of-the-art archaeological science techniques to support new discoveries about human evolution following recent controversies at a cave site in Africa, says a group of international experts. Their recommendations follow claims published in June of this year that Homo naledi --a small-brained human species -- buried their dead in Rising Star Cave, South Africa, between 335,000 and 241,000 years ago, and may also have decorated the cave walls with engravings.

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A recent trial of identical twins comparing vegan and omnivore diets found that a vegan diet improves overall cardiovascular health.