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Categories: Biology: Biochemistry, Geoscience: Environmental Issues

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Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier -- and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomized controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods -- and provides some benefits such as lowering blood sugar, which may be particularly important in people at risk of developing type 2 diabetes. The use of sweeteners in place of sugar in foods can be controversial due to conflicting reports about their potential to increase appetite. Previous studies have been carried out but did not provide robust evidence. However, the researchers say their study, which meets the gold standard level of proof in scientific investigation, provides very strong evidence that sweeteners and sweetness enhancers do not negatively impact appetite and are beneficial for reducing sugar intake.

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A research consortium provides evidence that social behavior and social status are reflected at the molecular level of gene activation (epigenome) in juvenile and adult free-ranging spotted hyenas. They analyzed non-invasively collected gut epithelium samples from both high-ranking and low-ranking female hyenas and showed that rank differences were associated with epigenetic signatures of social inequality, i.e., the pattern of activation or switching off of genes that regulate important physiological processes such as energy conversion and immune response in several genome regions.

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Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step in the development of drugs against the deadly disease.

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Through DNA sequencing of Tasmanian devils and their tumors, researchers have tracked the genomic interactions between the animals and the cancer.

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A recent study reveals an unexpected link between manganese -- a naturally occurring mineral -- and increased carbon emissions from high-latitude boreal forests. The study uncovers how manganese increases carbon emissions from boreal forest soil, over time, challenging conventional understanding of the role of manganese in the carbon cycle.

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A group of international experts has presented a blueprint for national indoor quality standards for public buildings. The experts addressed setting standards for three key indoor pollutants -- carbon dioxide, carbon monoxide, and PM2.5 (particles so small they can lodge deep in the lungs and enter the bloodstream) -- and ventilation rate.

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A new bioluminescence imaging technique has created highly detailed, and visually striking, images of the movement of oxygen in the brains of mice. The method, which can be easily replicated by other labs, will enable researchers to more precisely study forms of hypoxia in the brain, such as the denial of oxygen to the brain that occurs during a stroke or heart attack. The new research tool is already providing insight into why a sedentary lifestyle may increase risk for diseases like Alzheimer's.

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Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.

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Analysing the diversity of organic compounds dissolved in freshwater provides a reliable measure of ecosystem health, say scientists.

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Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.

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Researchers have found that parents with chemical intolerance are more likely to report children with autism and ADHD.

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A case study on the effects of open waste burning on air quality in Northwestern Greenland calls attention to the importance of no-one-left-behind sustainable air quality monitoring in the Arctic region.

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A breakthrough in sustainable molecular transformations has been announced. Chemists have developed an important way to harness the power of visible light to drive chemical processes with greater efficiencies, offering a greener alternative to traditional methods.

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An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.

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Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and hybrid material for targeted binding and separation of viral particles.

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How coral populations expand into new areas and sustain themselves over time is limited by the scope of modern observations. Going back thousands of years, a study provides geological insights into coral range expansions by reconstructing the composition of a Late Holocene-aged subfossil coral death assemblage in an unusual location in Southeast Florida and comparing it to modern reefs throughout the region. Findings offer a unique glimpse into what was once a vibrant coral reef assemblage and discover if history can repeat itself in the face of climate change.

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Ocean-atmosphere coupling, the exchange in energy between the ocean and atmosphere, influences teleconnection patterns, the climate effects across vast geographical areas. However, its impact outside the tropics is unclear. A group of researchers examined the effect of ocean coupling on atmospheric circulation patterns in the Northern Hemisphere. They found that extratropical ocean-atmosphere coupling enhances teleconnection patterns and causes more meandering westerly jet streams, which are linked to extreme weather events.

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Engineers designed an 'architected' reef that can mimic the wave-buffering effects of natural reefs while providing pockets for marine life. The sustainable and cost-saving structure could dissipate more than 95 percent of incoming wave energy using a small fraction of the material normally needed.

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New research finds that not all cattle are the same when it comes to grazing, and knowing that could lead to better animal health and range conditions.

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Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.