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Categories: Biology: Biochemistry, Geoscience: Earthquakes

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Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

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Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.

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A new study of rice paddy snakes in Southeast Asia gives key details to their diversification and natural history, adding molecular evidence that the rise of the Khorat Plateau and subsequent environmental shifts in Thailand may have altered the course of the snakes' evolution some 2.5 million years ago.

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Despite being scattered across more than a million square kilometers, new research has revealed that remote coral reefs across the Seychelles are closely related. Using genetic analyses and oceanographic modelling, researchers demonstrated for the first time that a network of ocean currents scatter significant numbers of larvae between these distant islands, acting as a 'coral superhighway.'

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An international team of palaeontologists applied recently developed methods to measure theropod (carnivorous) dinosaur species diversity. The newly applied method uses both traditional phylogenetic analysis, discriminant analysis as well as machine learning.

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A new article looked at 40 years of data collected on 40 pronghorn herds residing in the Wyoming Basin Shrub Steppe. Overall, 80% of the herds saw a decrease in productivity, and nearly 43% saw a significant decrease. After looking at a number of variables that could potentially contribute to the decline, the researchers identified the two most strongly associated: development of oil and gas resources and woody encroachment.

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Giraffes, with their bizarre body plan, have always held a special place in the minds of evolutionary biologists and non-experts alike. In a new study whole-genome sequencing data was used to investigate the evolutionary processes occurring within giraffes. In particular, the authors were interested in establishing whether different populations of giraffes really have been isolated from each other for extended periods of time, which is normally a requirement before new species can arise.

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Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern. It not only affects the health of those who suffer from it, but could also have serious consequences for their offspring. Scientists have studied the impact of maternal obesity on the risk of developing liver disease and liver cancer. Using an animal model, the team discovered that this risk was indeed much higher in the offspring of mothers suffering from obesity.

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Scientists have discovered the specific enzyme that a species of sandfly uses to produce a pheromone attractant, which could lead to the creation of targeted traps to control them and reduce the spread of the potentially fatal disease, Leishmaniasis.

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A team of researchers has uncovered a direct genetic link between fluorescence and color in sea anemones -- those soft and tentacled tide pool creatures often encountered by beachgoers.

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Grand-offspring of male frogs exposed to the pesticide linuron exhibited changes in their DNA that was linked to significant physiological impacts, a study reveals. The research highlights the profound transgenerational consequences of environmental pollution on amphibian populations, which are already under threat of extinction.

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Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

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Natural products have unique chemical structures and biological activities and can play a pivotal role in advancing pharmaceutical science. In a pioneering study, researchers discovered Inaoside A, an antioxidant derived from Laetiporus cremeiporus mushrooms. This breakthrough sheds light on the potential of mushrooms as a source of therapeutic bioactive compounds.

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Researchers have succeeded in identifying the odorants responsible for the characteristic lychee note of Muscaris grapes.

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Scientists reveal new lineages of giant sea anemones in Japan and their surprising associations with anemonefish.

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Researchers have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.

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Researchers have painstakingly taken computed topography (CT) scans of more than 13,000 individual specimens to create 3D images of more than half of all the world's animal groups, including mammals, fishes, amphibians and reptiles.

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New research describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos. The technique could be used by women of advanced maternal age or for those who are unable to produce viable eggs due to previous treatment for cancer or other causes. It also raises the possibility of men in same-sex relationships having children who are genetically related to both parents.

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Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.

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A team deciphers complicated mechanism underlying genetic diversity.