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Categories: Biology: Biochemistry, Environmental: Biodiversity
Published Mechanism discovered that protects tissue after faulty gene expression
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A study has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. Future research could lead to new therapeutic approaches to treat diseases caused by faulty splicing.
Published Rare 3D fossils show that some early trees had forms unlike any you've ever seen
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In the fossil record, trees typically are preserved with only their trunks. They don't usually include any leaves to show what their canopies and overall forms may have looked like. In a new study, researchers describe fossilized trees from New Brunswick, Canada with a surprising and unique three-dimensional crown shape.
Published How leafcutter ants cultivate a fungal garden to degrade plants and provide insights into future biofuels
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Scientists developed a new method to map exactly how a fungus works with leafcutter ants in a complex microbial community to degrade plant material at the molecular level. The team's insights are important for biofuels development.
Published Disrupted cellular function behind type 2 diabetes in obesity
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Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.
Published A clutch stretch goes a long way
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New results reveal a new mode of force transmission in which dynamic molecular stretching bridges the extracellular matrix and flowing F-actin moving at different speeds. This discovery underscores the necessity of molecular elasticity and random coupling for sufficiently transmitting force. The findings also call for revising the role of molecular unfolding.
Published Zebrafish navigate to find their comfortable temperature
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Zebrafish are smaller than your little finger, with a brain no more than half the size of a pinhead. Yet these animals possess an efficient navigation system that enables them to find their way back to spots in the water where the temperature suits them.
Published The arrangement of bacteria in biofilms affects their sensitivity to antibiotics
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Many bacteria form an antibiotic-resistant slime. Research detailing that slime's structure could help lead to new treatments.
Published Active components of ginkgo biloba may improve early cognitive recovery after stroke
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Adults treated with 14 days of intravenous injections of ginkgo diterpene lactone meglumine (GDLM) -- a combination of biologically active components of ginkgo biloba -- after an ischemic (clot-caused) stroke had better cognitive recovery at 14 days and 90 days.
Published Resistant bacteria can remain in the body for years
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Fighting disease-causing bacteria becomes more difficult when antibiotics stop working. People with pre-existing conditions in particular can carry resistant germs and suffer from repeated infections for years, according to a new study.
Published Plant receptors that control immunity and development share a common origin
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Researchers have traced the origin and evolutionary trajectory of plant immune receptors. Their discovery will make it easier to identify immune receptor genes from genomic information and could help in the development of pathogen-resistant crops.
Published Gut bacteria can process dietary fiber into an anti-allergy weapon
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Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.
Published Mussel-inspired antimicrobial coating protects sanitary fabrics from infections
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Researchers have developed an innovative material to fight against the spread of pathogens, infections and antimicrobial resistance. Inspired by the substances secreted by mussels to adhere to rocks, it can be used as a coating to protect healthcare fabrics and provides an effective alternative to commonly used materials such as paper, cotton, surgical masks and commercial plasters.
Published LSH genes associated with defining the shapes of stems, flowers and leaves required for N-fixing root nodules
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The developmental regulators that confer the identity of N-fixing root nodules belong to a transcription factor family (LSH) more commonly associated with defining the shapes of stems, flowers and leaves.
Published Microbial research unravels a global nitrogen mystery
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A research findings show that different AOM lineages employ different regulatory strategies for ammonia or urea utilization, thereby minimizing direct competition with one another and allowing for coexistence.
Published Shining a new light on the tug-of-war between virus and host
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The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.
Published Climate change threatens older elephants most, jeopardizing African elephants' future
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A collaborative team of researchers has conducted first-of-its kind research into how global climate change affects African elephants. The work shows that older elephants will have markedly decreased chances of survival, which will not only drastically reduce the species' overall ability to weather the changing climate but will send ripple effects throughout the surrounding landscape. The team has also modeled possible mitigation scenarios.
Published Discovery of a third RNA virus linage in extreme environments Jan 17, 2024
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A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.
Published Groundbreaking genome editing tools unlock new possibilities for precision medicine
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A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Published Fungal-rich soil may improve green roofs
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Green roofs have become increasingly popular thanks to their benefits related to climate adaptation, mitigation, and urban biodiversity management. But, in the U.S., green roofs are typically planted with non-native plants in sterile soils, and their effectiveness declines over time. A new study finds that managing green roof soil microbes boosts healthy urban soil development, which is a methodology that could be applied to support climate resilience in cities.
Published How seahorse-like toxins kill insects
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Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.