Showing 20 articles starting at article 821

< Previous 20 articles        Next 20 articles >

Categories: Biology: Biochemistry, Mathematics: Statistics

Return to the site home page

     (via sciencedaily.com)     Original source 

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

     (via sciencedaily.com)     Original source 

It is one of the world's most spectacular sights -- huge flocks or 'flamboyances' of flamingos around East Africa's lakes -- as seen in the film Out of Africa or David Attenborough's A Perfect Planet. But new research has revealed how the lesser flamingo is at danger of being flushed out of its historic feeding grounds, with serious consequences for the future of the species.

     (via sciencedaily.com)     Original source 

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV infection.

     (via sciencedaily.com)     Original source 

Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

     (via sciencedaily.com)     Original source 

Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.

     (via sciencedaily.com)     Original source 

Researchers have created a method that extracts over 80 percent of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain.

     (via sciencedaily.com)     Original source 

Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.

     (via sciencedaily.com)     Original source 

Traces of DNA in the stomachs of predatory snails give a team og geobiologists new insights into the ecology of placozoans.

     (via sciencedaily.com)     Original source 

Ant species living in Boulder's foothills have shifted their habitat over the last six decades, potentially affecting local ecosystems, suggests a new study.

     (via sciencedaily.com)     Original source 

Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.

     (via sciencedaily.com)     Original source 

Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

     (via sciencedaily.com)     Original source 

A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

     (via sciencedaily.com)     Original source 

Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.

     (via sciencedaily.com)     Original source 

Researchers decode repair mechanism during transcription of genetic information.

     (via sciencedaily.com)     Original source 

A survey of orchid bees in the Brazilian Amazon, carried out in the 1990s, is shedding new light the impact of deforestation on the scent-collecting pollinators, which some view as bellwethers of biodiversity in the neotropics.

     (via sciencedaily.com)     Original source 

Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water. The development provides a platform for the industrial-scale, tunable production of a material that holds great potential for turning the plastic industry green.

     (via sciencedaily.com)     Original source 

Fish and invertebrate animals are far more affected by warmer and more acidic seawater than was previously known. The big gain of the new method is that more details become known about effects of climate change on species.

     (via sciencedaily.com)     Original source 

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

     (via sciencedaily.com)     Original source 

Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.

     (via sciencedaily.com)     Original source 

Researchers have developed a new method to predict the financial impacts climate change will have on agriculture, which can help support food security and financial stability for countries increasingly prone to climate catastrophes.