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Categories: Biology: Biochemistry, Mathematics: Statistics

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To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code. Now, in a study using blood samples from men and women with HIV on long-term suppressive therapy, a team of scientists reports new evidence that one such stable reservoir of HIV genomes can be found in circulating white blood cells called monocytes.

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Squids and octopuses are masters of camouflage. But some aspects of how they become reversibly transparent are still 'unclear,' because researchers can't culture cephalopod skin cells in the lab. Now, researchers have replicated the tunable transparency of squid skin in mammalian cells, which are more easily cultured.

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A new discovery changes ideas about the origin of branching in plants.

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Phosphorus is a natural mineral found in fertilizer that is essential for plant growth and development, and Earth's agricultural-grade phosphorus reserves are expected to be depleted in 50 to 100 years. A new discovery is changing their understanding of iron toxicity in plants caused by low phosphorus levels.

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Chemists use high-precision quantum chemistry to study key elements of super-efficient energy transfer in an important element of photosynthesis.

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A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells -- providing clues to their function and helping to identify potential drug targets.

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Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report. As noted by the authors, the results support further development of their vaccine platform, LIONTM/repRNA, for maternal and neonatal settings to protect against mother-to-child transmission of pathogens in animals and humans.

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MitoQ, a mitochondrial antioxidant that is available to the public as a diet supplement, was found in a mouse study to reverse the detrimental effects that HIV and antiretroviral therapy (ART) have on mitochondria in the brain, heart, aorta, lungs, kidney and liver.

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A group of natural history museums has mapped the total collections from 73 of the world's largest natural history museums in 28 countries. This is the first step of an ambitious effort to inventory global holdings that can help scientists and decision makers find solutions to urgent, wide-ranging issues such as climate change, food insecurity, human health, pandemic preparedness, and wildlife conservation.

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The medicinal secrets of the Chilean soapbark tree have been laid bare, unlocking a future of more potent, affordable, and sustainably sought vaccines. Researchers have taken a major step forward in addressing this problem, by using a combination of genome mining and bioengineering techniques to produce saponin-based vaccine adjuvants in the laboratory without harvesting material directly from trees.

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Physicists have developed a dynamical model of animal behavior that may explain some mysteries surrounding associative learning going back to Pavlov's dogs.

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Microplastic pollution reduces energy production in a microscopic creature found in freshwater worldwide, new research shows.

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Researchers have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB. If this natural process can be harnessed with new treatments, it could present an alternative to, or improve use of antibiotics, especially where bacteria have become resistant to existing drugs.

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Researchers have uncovered a key role for a new type of cell in touch detection in the skin of the fruit fly.

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Damage in the human genome can be repaired. But this works better in germ cells, sperm and eggs, than in normal body cells. Responsible for this is the DREAM protein complex, which prevents the activation of all available repair mechanisms. A research team has now shown that normal body cells can also be repaired better once this complex has been deactivated. In the long run, the scientists hope to develop better therapies to prevent cancer and aging-associated diseases.

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At least 80% of sites identified as being internationally important for biodiversity on land currently contain infrastructure -- of which more than 75% contain roads. In the future, more sites that are important for biodiversity could contain powerplants, mines and oil and gas infrastructure.

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Applying hydrostatic pressure as an external stimulus, researchers demonstrate a new way to regulate singlet fission (SF), a process in which two electrons are generated from a single photon, in chromophores, opening doors to the design of SF-based materials with enhanced (photo)energy conversion. Their method overrides the strict requirements that limit the molecular design of such materials by realizing an alternative control strategy.

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Scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet. Key to this breakthrough is miRNA, a molecule nearly 200,000 times smaller than the width of a human hair.

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Continued warming of the climate would see a rise in the number and spread of potentially fatal infections caused by bacteria found along parts of the coast of the United States. Vibrio vulnificus bacteria grow in warm shallow coastal waters and can infect a cut or insect bite during contact with seawater. The researchers predict that by 2041--2060 infections may spread to encompass major population centers around New York. Combined with a growing and increasingly elderly population, who are more susceptible to infection, annual case numbers could double.

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Some plants can survive months without water, only to turn green again after a brief downpour. A recent study shows that this is not due to a 'miracle gene.' Rather, this ability is a consequence of a whole network of genes, almost all of which are also present in more vulnerable varieties.