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Categories: Biology: Biochemistry, Mathematics: Modeling
Published New study confirms presence of flesh-eating and illness-causing bacteria in Florida's coastal waters following Hurricane Ian
(via sciencedaily.com) Original source When Hurricane Ian struck southwest Florida in September 2022, it unleashed a variety of Vibrio bacteria that can cause illness and death in humans, according to a new study.
Published Peering inside cells to see how they respond to stress
(via sciencedaily.com) Original source The heat shock response of cells is a classic model of biological adaptation, part of the fundamental processes of life -- conserved in creatures from single-celled yeast to humans -- that allow our cells to adjust to changing conditions in their environment. For years, scientists have focused on how different genes respond to heat stress to understand this survival technique. Now, thanks to the innovative use of advanced imaging techniques, researchers are getting an unprecedented look at the inner machinery of cells to see how they respond to heat stress.
Published Climate change coping mechanism discovered in humble algae
(via sciencedaily.com) Original source One of the building blocks of ocean life can adapt to cope with the effects of climate change, according to new research. The discovery holds promises for biotechnology developments that could counter the negative effects of changing environmental conditions, such as ocean warming and even the reduction in the productivity of crops.
Published Fecal microbe transplants: B. vulgatus genes that correlate with early colonization
(via sciencedaily.com) Original source Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant. Most failures of fecal microbe transplantation occur in the first four weeks. Researchers have now found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.
Published 200-year-old DNA helps map tiny fly's genetic course to new lands, modern times
(via sciencedaily.com) Original source Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.
Published Scientists generate first single-cell 'atlas' of the primate brain to help explore links between molecules, cells, brain function and disease
(via sciencedaily.com) Original source As part of the effort to better understand the evolution of the brains in people and animals, a research team has generated the world's largest primate brain-wide atlas.
Published Coffee and cocoa plants at risk from pollinator loss
(via sciencedaily.com) Original source Tropical crops such as coffee, cocoa, watermelon and mango may be at risk due to the loss of insect pollinators, finds a new study.
Published Scientists unveil detailed cell maps of the human brain and the nonhuman primate brain
(via sciencedaily.com) Original source A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.
Published Engineered bacteria paint targets on tumors for cancer-killing T cells to see
(via sciencedaily.com) Original source Synthetic biologists report on a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.
Published Honey bees may inherit altruistic behavior from their mothers
(via sciencedaily.com) Original source True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.
Published Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method
(via sciencedaily.com) Original source To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.
Published New organ-on-a-chip model of human synovium could accelerate development of treatments for arthritis
(via sciencedaily.com) Original source The synovium is a membrane-like structure that lines the knee joint and helps to keep the joint happy and healthy, mainly by producing and maintaining synovial fluid. Inflammation of this tissue is implicated in the onset and progression of arthritic diseases such as rheumatoid and osteoarthritis. Therefore, treatments that target the synovium are promising in treating these diseases. However, we need better models in the laboratory that allow us to find and test new treatments. We have developed an organ-on-a-chip based model of the human synovium, and its associated vasculature, to address this need.
Published Omega-3 discovery moves us closer to 'precision nutrition' for better health
(via sciencedaily.com) Original source Researchers have obtained new insights into how African-American and Hispanic-American people’s genes influence their ability to use Omega-3 and Omega-6 fatty acids for good health. The findings are an important step toward “precision nutrition” – where a diet tailored to exactly what our bodies need can help us live longer, healthier lives.
Published A step towards AI-based precision medicine
(via sciencedaily.com) Original source Artificial intelligence, AI, which finds patterns in complex biological data could eventually contribute to the development of individually tailored healthcare. Researchers have developed an AI-based method applicable to various medical and biological issues. Their models can for instance accurately estimate people's chronological age and determine whether they have been smokers or not.
Published Using different flours for sourdough fosters different bacteria -- and flavors
(via sciencedaily.com) Original source A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.
Published Study clearly identifies nutrients as a driver of the Great Atlantic Sargassum Belt
(via sciencedaily.com) Original source Under normal conditions, the floating macroalgae Sargassum spp. provide habitat for hundreds of types of organisms. However, the Great Atlantic Sargassum Belt (GASB) that emerged in 2011 has since then caused unprecedented inundations of this brown seaweed on Caribbean coastlines, with harmful effects on ecosystems while posing challenges to regional economies and tourism, and concerns for respiratory and other human health issues.
Published An AI tool that can help forecast viral outbreaks
(via sciencedaily.com) Original source EVEscape predicts future viral mutations, new variants using evolutionary, biological information.
Published Fruit fly serenade: Neuroscientists decode their tiny mating song
(via sciencedaily.com) Original source An extremely supportive atmosphere for new ideas laid the foundation for an 'Aha moment' about a toggle-switch in the fruit fly brain. Do humans have one, too?
Published Doubling down on known protein families
(via sciencedaily.com) Original source A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'
Published Evolutionary secrets of 'Old Tom' and the killer whales of Eden revealed by genetic study
(via sciencedaily.com) Original source Evolutionary biologists have for the first time decoded the genetic lineage of a famous killer whale and a pod that once worked alongside whale hunters off the coast of Australia. In the Australian tradition of claiming New Zealand's celebrities as its own, Old Tom, the leader of a pod of killer whales that famously helped whalers hunt baleen whales in the 20th century, has ancestral links to modern-day killer whales in New Zealand, according to new DNA research. Old Tom also shared a common ancestor with killer whales from Australasia, the North Pacific, and North Atlantic Oceans, but is most similar to modern New Zealand killer whales. However, most of Tom's DNA code is not found in other killer whales globally suggesting that the killer whales of Eden may have become extinct locally.