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Categories: Biology: Biochemistry, Physics: General

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Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer. Now, a new study introduces an original technique, called HiDEF-seq, that can accurately detect the early molecular changes in DNA code that precede mutations.

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Researchers have reconstructed the evolutionary history and global spread of malaria over the past 5,500 years, identifying trade, warfare, and colonialism as major catalysts for its dispersal.

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Over 17 million insects migrate each year through a single mountain pass on the border between France and Spain, new research shows.

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Inspired by the material that makes up oyster and abalone shells, engineers have created a new cement composite that is 17 times more crack-resistant than standard cement and 19 times more able to stretch and deform without breaking. The findings could eventually help increase the crack resistance of a wide range of brittle ceramic materials from concrete to porcelain.

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Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates 21.4% more oil than ordinary camelina.

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Haiku poems have reflected humans' experiences in nature for hundreds of years, including observations of bugs and other wildlife. Recently, researchers analyzed which insects were mentioned the most in haiku -- with butterflies, fireflies and singing insects such as crickets topping the list.

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Researchers tracked how plant matter moves through bacteria's metabolism. Microbes respire three times as much carbon dioxide (CO2) from non-sugar carbons from lignin compared to sugar from cellulose. Although microbes consume both types of plant matter at the same time, each type enters a different metabolic pathway. Findings could improve predictions of how climate-dependent changes in soil carbon types will affect microbial CO2 production.

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The exhaust heat generated by a fusing plasma in a commercial-scale reactor may not be as damaging to the vessel's innards as once thought, according to new research about escaping plasma particles.

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Researchers have discovered that virus-like nanoparticles can promote the multicellular organization and reproduction of host bacteria. These particles, which are evolutionarily related to phages (viruses that infect bacteria), contain an enzyme that helps shape the multicellular architecture and ultimately enhances morphological differentiation.

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The need to transition away from fossil fuels to more sustainable energy production is critical. That's why a team of researchers is looking at a potential power source that not only produces no carbon emissions but removes carbon as it works: algae.

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To help probe the mystery of how brains control movement, scientists have created a virtual rat with an artificial brain that can move around just like a real rodent. The researchers found that activations in the virtual control network accurately predicted neural activity measured from the brains of real rats producing the same behaviors.

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An international scientific team has redefined our understanding of archaea, a microbial ancestor to humans from two billion years ago, by showing how they use hydrogen gas. The findings explain how these tiny lifeforms make energy by consuming and producing hydrogen. This simple but dependable strategy has allowed them to thrive in some of Earth's most hostile environments for billions of years.

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Researchers have demonstrated a new method that could enable the large-scale manufacturing of optical qubits. The advance could bring us closer to a scalable quantum computer.

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A study revealed that a simple thermal reaction of gallium nitride with metallic magnesium results in the formation of a distinctive superlattice structure. This represents the first time researchers have identified the insertion of 2D metal layers into a bulk semiconductor. By carefully observing materials through various cutting-edge characterization techniques, the researchers uncovered new insights into the process of semiconductor doping and elastic strain engineering.

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Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment.

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Physicists have calculated how suitable molecules can be stimulated by infrared light pulses to form tiny magnetic fields. If this is also successful in experiments, the principle could be used in quantum computer circuits.

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A common type of ocean algae plays a significant role in producing a massively abundant compound that helps cool the Earth's climate, new research has discovered.

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Researchers have found that the maturation of the senses for smell and touch is closely linked in mice and that this strong interaction takes place within a narrow developmental time window. These findings not only underline the importance of environmental stimuli for brain assembly in early life, but also the interdependent development of the senses.

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A discovery could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.

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Researchers examined anatomy of neurons from humans, mice and fruit flies. They discovered that the cellular structure of the brain is at a critical point, poised between two phases. New insights could help design computational models of the brain's complexity.