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Categories: Biology: Biochemistry, Physics: General

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The heat shock response of cells is a classic model of biological adaptation, part of the fundamental processes of life -- conserved in creatures from single-celled yeast to humans -- that allow our cells to adjust to changing conditions in their environment. For years, scientists have focused on how different genes respond to heat stress to understand this survival technique. Now, thanks to the innovative use of advanced imaging techniques, researchers are getting an unprecedented look at the inner machinery of cells to see how they respond to heat stress. 

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One of the building blocks of ocean life can adapt to cope with the effects of climate change, according to new research. The discovery holds promises for biotechnology developments that could counter the negative effects of changing environmental conditions, such as ocean warming and even the reduction in the productivity of crops. 

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Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant. Most failures of fecal microbe transplantation occur in the first four weeks. Researchers have now found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.

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Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.

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As part of the effort to better understand the evolution of the brains in people and animals, a research team has generated the world's largest primate brain-wide atlas.    

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Tropical crops such as coffee, cocoa, watermelon and mango may be at risk due to the loss of insect pollinators, finds a new study.

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A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.

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Synthetic biologists report on a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.

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True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.

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Physicists have shown that simulating models of hypothetical time travel can solve experimental problems that appear impossible to solve using standard physics.

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The amount of power a microswimmer needs to move can now be determined more easily. Scientists developed a general theorem to calculate the minimal energy required for propulsion. These insights allow a profound understanding for practical applications, such as targeted transport of molecules and substrates.

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To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.

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In a surprising new study, researchers have found that the electron beam radiation that they previously thought degraded crystals can actually repair cracks in these nanostructures. The groundbreaking discovery provides a new pathway to create more perfect crystal nanostructures, a process that is critical to improving the efficiency and cost-effectiveness of materials that are used in virtually all electronic devices we use every day.

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Researchers have long been exploring the effect of using tailored laser drives to manipulate the properties of quantum materials away from equilibrium. One of the most striking demonstrations of these physics has been in unconventional superconductors, where signatures of enhanced electronic coherences and super-transport have been documented in the resulting non-equilibrium states. However, these phenomena have not yet been systematically studied or optimized, primarily due to the complexity of the experiments. Technological applications are therefore still far removed from reality. In a recent experiment, this same group of researchers discovered a far more efficient way to create a previously observed metastable, superconducting-like state in K3C60 using laser light.

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Transition metal dichalcogenide (TMD) semiconductors are special materials that have long fascinated researchers with their unique properties. For one, they are flat, one-atom-thick two-dimensional (2D) materials similar to that of graphene. They are compounds that contain different combinations of the transition metal group (e.g., molybdenum, tungsten) and chalcogen elements (e.g., sulfur, selenium, tellurium).

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Researchers have obtained new insights into how African-American and Hispanic-American people’s genes influence their ability to use Omega-3 and Omega-6 fatty acids for good health. The findings are an important step toward “precision nutrition” – where a diet tailored to exactly what our bodies need can help us live longer, healthier lives.

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A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.

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Under normal conditions, the floating macroalgae Sargassum spp. provide habitat for hundreds of types of organisms. However, the Great Atlantic Sargassum Belt (GASB) that emerged in 2011 has since then caused unprecedented inundations of this brown seaweed on Caribbean coastlines, with harmful effects on ecosystems while posing challenges to regional economies and tourism, and concerns for respiratory and other human health issues.

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EVEscape predicts future viral mutations, new variants using evolutionary, biological information.  

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An extremely supportive atmosphere for new ideas laid the foundation for an 'Aha moment' about a toggle-switch in the fruit fly brain. Do humans have one, too?