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Categories: Biology: Developmental, Paleontology: Early Mammals and Birds

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A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.

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A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

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The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.

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What distinguishes the growth and development patterns of early mammals of the Jurassic period? Paleontologists have been able to gauge the lifespan and growth rates of these ancient animals, and even when they reached maturity, by studying growth rings in fossilized tooth roots.

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A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.

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In nematodes and humans, mitochondrial stress in the nervous system initiates a whole-body response that is most pronounced in the gut. A recent study showed that in nematodes, the odor of a pathogen triggers the nervous system to broadcast this response to the rest of the organism, prepping mitochondria in intestinal cells to fight a bacterial infection. Humans, too, may be able to sense pathogenic odors that prepare the gut for an infection.

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Mammoths, the massive pre-historic ice age cousins of the modern-day elephant, have always been understood to have inhabited parts of British Columbia, but the question of when has always been a bit woolly. Now, a new study has given scientists the clearest picture yet when the giant mammals roamed Vancouver Island.

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The pterosaur likely used all four limbs to propel itself in the air, as seen in bats today, researchers have found.

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With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.

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Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils. This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.

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The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.

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A tiny fossil penguin plays a huge role in the evolutionary history of the bird, an international study shows.

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Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.

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Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.

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Study finds that the mass extinction caused by an asteroid about 66 million years ago led to critical changes in bird genomes that ultimately sparked the incredibly diversity living birds.

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Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.

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A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. This technology could significantly improve research on proteins in living organisms and opens up new possibilities for medical research.

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Researchers have modified certain bacteria with UV light so that they produce more cellulose. The basis for this is a new approach with which the researchers generate thousands of bacterial variants and select those that have developed into the most productive.

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A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.

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Birds tend to be more colorful in the tropics, and scientists wanted to find out how they got there: if colorful feathers evolved in the tropics, or if tropical birds have brightly-colored ancestors that came to the region from somwhere else. Scientists built a database of 9,409 birds to explore the spread of color across the globe. They found that iridescent, colorful feathers originated 415 times across the bird tree of life, and in most cases, arose outside of the tropics -- and that the ancestor of all modern birds likely had iridescent feathers, too.