Showing 20 articles starting at article 1421
Categories: Biology: Developmental, Geoscience: Geography
Published Pioneering approach advances study of CTCF protein in transcription biology


Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein.
Published Scientists discover the evolutionary secret behind different animal life cycles


Researchers uncover for the first time the mechanism that likely explains how embryos form either a larva or a miniature version of the adult.
Published Actin affects the spread of cancer in several ways


The transport of molecules along the cell's skeleton plays a role in cancer metastasis, researchers show.
Published How cells prevent harmful extra DNA copies


A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study. The work solves a mystery that has long puzzled biologists.
Published Botany: Chloroplast from the father


Under cold conditions, not only the mother plant but also the father plant can pass on its chloroplasts to the offspring.
Published Genome editing procedures optimized


Scientists succeed in boosting the efficiency of CRISPR/Cas9 and related methods and modifying initially inaccessible DNA sequences. They fine-tuned these tools to enable effective genetic screening for modelling specific gene mutations.
Published New genetic disorder that causes susceptibility to opportunistic infections


Immunogeneticists have discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.
Published DNA from domesticated chickens is tainting genomes of wild red junglefowl, study finds


The red junglefowl -- the wild ancestor of the chicken -- is losing its genetic diversity by interbreeding with domesticated birds, according to a new study.
Published An Old Yellow Enzyme helps algae combat photooxidative stress


Old Yellow Enzymes (OYEs) were discovered in the 1930s and have been the subject of much research ever since. This is because these biocatalysts -- coloured yellow by an auxiliary molecule -- are capable of performing reactions that are very valuable for the chemical industry, such as producing drug precursors or fragrances. Even though OYEs are found in many organisms, their natural role for these organisms has hardly been understood so far -- possibly because the research focus has been on their biotechnological application. Researchers have now shown that an OYE of the unicellular green alga Chlamydomonas reinhardtii is vital for this plant microorganism to protect itself from photooxidative stress.
Published New study decodes one of the living world's fastest cell movements



Heliozoan axopodia are important for their motility. However, the underlying mechanism of their axopodial contraction has remained ambiguous. Recently, researchers have reported that microtubules are simultaneously cleaved at multiple sites, allowing the radiating axopodia in a heliozoan, Raphidocystis contractilis, to disappear almost instantly. They have now identified the gene set and proteins involved in this microtubule disruption. This research can help develop a method to detect water pollution and evaluate the efficacy of new anticancer drugs.
Published Modified CRISPR-based enzymes improve the prospect of inserting entire genes into the genome to overcome diverse disease-causing mutations



Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly.