Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells      (via sciencedaily.com)     Original source 

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.  Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.

Biology: Biochemistry Biology: General Biology: Microbiology Environmental: Ecosystems Environmental: Water Geoscience: Earth Science Geoscience: Geochemistry Geoscience: Geology Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

Yucatán's underwater caves host diverse microbial communities      (via sciencedaily.com)     Original source 

With help from an experienced underwater cave-diving team, researchers have constructed the most complete map to date of the microbial communities living in the submerged labyrinths beneath Mexico's Yucatán Peninsula. Researchers found the cave system's microbiome is distinct from the nearby sea, and microbial communities vary between cave systems forming distinct 'neighborhoods.'  

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular
Published

The mystery of phosphite -- a scientific detective story      (via sciencedaily.com)     Original source 

Biologists have discovered a phosphorus-based bacterial metabolism that is both new and ancient. In a special role: a calculation from the 1980s, a sewage plant, a new bacterial organism, and a remnant from around 2.5 billion years ago.    

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Yeast cells can produce drugs for treatment of psychotic disorders      (via sciencedaily.com)     Original source 

An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

Biology: General Biology: Zoology Ecology: Animals Environmental: Biodiversity Geoscience: Geography Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
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Found at last: Bizarre, egg-laying mammal finally rediscovered after 60 years      (via sciencedaily.com)     Original source 

A long-beaked echidna named after Sir David Attenborough and last seen by scientists in 1961 has been photographed for the first time in an Indonesian tropical forest. An international team of researchers worked with local communities to deploy over 80 camera traps to film the elusive animal. Besides rediscovering the echidna, the team uncovered a wealth of species completely new to science, including beetles, spiders, and a remarkable tree-dwelling shrimp.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Team creates synthetic enzymes to unravel molecular mysteries      (via sciencedaily.com)     Original source 

A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.

Biology: Biochemistry Biology: Biotechnology Biology: General Biology: Microbiology Chemistry: Biochemistry Chemistry: General
Published

New way to count microbes speeds research, cuts waste, could lead to new antibiotics      (via sciencedaily.com)     Original source 

Researchers have developed a new way of counting microorganisms that works as much as 36 times faster than conventional methods, cuts plastic use more than 15-fold and substantially decreases the cost and carbon footprint of biomedical research. The technique could revolutionize the way microbiology experiments are conducted, allowing researchers to test potential new antibiotics in a fraction of the time.

Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Microbiology Ecology: Nature Environmental: Ecosystems Geoscience: Geochemistry
Published

Bacteria-virus arms race provides rare window into rapid and complex evolution      (via sciencedaily.com)     Original source 

Rather than a slow, gradual process as Darwin envisioned, biologists can now see how evolutionary changes unfold on much more accelerated timescales. Using an accelerated arms race between bacteria and viruses, researchers are documenting rapid evolutionary processes in simple laboratory flasks in only three weeks.

Biology: General Biology: Zoology
Published

Desert birds lay larger eggs when they have more helpers      (via sciencedaily.com)     Original source 

Desert birds lay larger eggs when they have more helpers to feed their chicks, new research shows.

Biology: General Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: General
Published

Palaeo-CSI: Mosasaurs were picky eaters      (via sciencedaily.com)     Original source 

Mosasaurs, those large marine reptiles from the long-gone Cretaceous world, were quite picky in their choice of diet. Researchers came to this conclusion after studying the wear marks on mosasaur teeth.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Chemistry: Biochemistry
Published

A breath of fresh air keeps drug-producing cells alive longer      (via sciencedaily.com)     Original source 

Researchers have developed a novel device that produces oxygen inside of a 'living pharmacy' implant in order to keep cells alive inside the self-contained device. The device produses oxygen through a smart, energy-efficient version of water splitting. In new experiments, the novel device kept cells (70-80%) alive for close to a month in low oxygen conditions in vitro, or weeks in vivo.

Biology: Biochemistry Biology: General Biology: Microbiology
Published

Early life exposure to broccoli sprouts protects against colitis in inflammatory bowel disease      (via sciencedaily.com)     Original source 

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD).

Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Zoology
Published

Poison dart frogs: Personality determines reproductive strategies      (via sciencedaily.com)     Original source 

Unlike their relatives, individuals of the poison frog Allobates femoralis are not poisonous but are captivating due to their different behavioral profiles: They successfully reproduce with different strategies depending on whether they are bold, aggressive or explorative. In addition, certain character traits are already present in this species at the tadpole stage.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

First live birth of a chimeric monkey using embryonic stem cell lines      (via sciencedaily.com)     Original source 

A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.

Biology: Biochemistry Biology: Cell Biology Biology: General
Published

Reducing vitamin B5 slows breast cancer growth in mice      (via sciencedaily.com)     Original source 

Researchers have discovered that breast cancer cells expressing a cancer-driving gene heavily rely on vitamin B5 to grow and survive.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life      (via sciencedaily.com)     Original source 

While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

Artificial bladders shine light on bugs that cause urinary tract infections      (via sciencedaily.com)     Original source 

A new study reveals that numerous bacterial strains are capable of hiding in the human bladder wall, suggesting why urinary tract infections often persist after treatment.