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Categories: Biology: General, Offbeat: Earth and Climate
Published Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
(via sciencedaily.com) Original source About a decade ago, researchers began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes. Not good if the objective of the project was to harness the metabolism of living bacteria to produce electricity.
Published TB vaccine shrinks liver cancer tumors in mice
(via sciencedaily.com) Original source Could the TB vaccine be a new immunotherapy for liver cancer? A study found that the century-old vaccine reduced tumors and extended survival for mice with liver cancer.
Published Utah's Bonneville Salt Flats has long been in flux
(via sciencedaily.com) Original source It has been long assumed that Utah's Bonneville Salt Flats was formed as its ancient namesake lake dried up 13,000 years ago. But new research has gutted that narrative, determining these crusts did not form until several thousand years after Lake Bonneville disappeared, which could have important implications for managing this feature that has been shrinking for decades to the dismay of the racing community and others who revere the saline pan 100 miles west of Salt Lake City. Relying on radiocarbon analysis of pollen found in salt cores, the study concludes the salt began accumulating between 5,400 and 3,500 years ago, demonstrating how this geological feature is not a permanent fixture on the landscape.
Published Snaking toward a universal antivenom
(via sciencedaily.com) Original source Scientists discovered antibodies that protect against a host of lethal snake venoms.
Published Increasingly similar or different? Centuries-long analysis suggests biodiversity is differentiating and homogenizing to a comparable extent
(via sciencedaily.com) Original source The tendency of communities and the species within them to become more similar or more distinct across landscapes -- biotic homogenization and differentiation -- are approximately balanced, according to a new study. This analysis is the first of its kind to provide a comprehensive assessment of how local and regional biodiversity changes combine across landscapes over centuries.
Published Revealing what makes bacteria life-threatening
(via sciencedaily.com) Original source Researchers have discovered that a mutation in the cellulose making machinery of E. coli bacteria allows them to cause severe disease in people -- 'good' bacteria make cellulose and 'bad' bacteria can't. The mutations stopped the E. coli making the cell-surface carbohydrate cellulose and this led to increased inflammation in the intestinal tract of the host, resulting in a breakdown of the intestinal barrier, so the bacteria could spread through the body. Understanding how bacteria spread from intestinal reservoirs to the rest of the body is important in preventing infections and tackling antibiotic resistance.
Published Weedy rice gets competitive boost from its wild neighbors
(via sciencedaily.com) Original source Weedy rice is an agricultural pest with a global economic impact. It is an aggressive weed that outcompetes cultivated rice and causes billions of dollars in yield losses worldwide. A study offers new insights into genetic changes that give weedy rice its edge over cultivated rice in tropical regions of the world.
Published Butterfly and moth genomes mostly unchanged despite 250 million years of evolution
(via sciencedaily.com) Original source Comparison of over 200 high-quality butterfly and moth genomes reveals key insights into their biology, evolution and diversification over the last 250 million years, as well as clues for conservation.
Published Citizen science to mitigate the environmental crisis in the marine environment
(via sciencedaily.com) Original source Citizen science can help to improve conservation and management strategies for Mediterranean marine ecosystems, and to mitigate the impact of the environmental crisis.
Published An awkward family reunion: Sea monsters are our cousins
(via sciencedaily.com) Original source The sea lamprey, a 500-million-year-old animal with a sharp-toothed suction cup for a mouth, is the thing of nightmares. A new study discovered that the hindbrain -- the part of the brain controlling vital functions like blood pressure and heart rate -- of both sea lampreys and humans is built using an extraordinarily similar molecular and genetic toolkit.
Published Mercury levels in tuna remain nearly unchanged since 1971
(via sciencedaily.com) Original source Tuna is one of the most popular seafoods worldwide. But this protein-rich fish can build up high levels of methylmercury from feeding on contaminated prey, like smaller fish or crustaceans. Despite efforts to reduce mercury emissions into the environment, researchers report that levels in tuna appear to be unchanged since 1971. They warn that more aggressive emission reduction targets are needed to start nudging down tuna mercury levels.
Published Compounds in female ginseng could lead to new osteoporosis treatments
(via sciencedaily.com) Original source With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic bone disease, they can be expensive and have side effects, limiting their availability to some people. In the search for alternative drug candidates, researchers have discovered and fully replicated a compound from a botanical source, female ginseng, that had potent anti-osteoporotic activity in cellular tests.
Published Kiss-and-tell: A new method for precision delivery of nanoparticles and small molecules to individual cells
(via sciencedaily.com) Original source The delivery of experimental materials to individual cells with exactness and exclusivity has long been an elusive and much sought-after ability in biology. With it comes the promise of deciphering many longstanding secrets of the cell. A research team has now successfully shown how small molecules and single nanoparticles can be applied directly onto the surface of cells. In the study the scientists describe their technique as a ' kiss' (microkiss) -- an easy and cost-effective new method, unlocking new possibilities in single-cell science with a view towards next generation therapeutic applications.
Published Toxic elements found in stranded whales, dolphins over 15 years
(via sciencedaily.com) Original source Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples collected from 90 whales and dolphins stranded in Georgia and Florida from 2007 to 2021.
Published Links between human, canine brain tumors
(via sciencedaily.com) Original source Researchers have discovered that meningiomas -- the most common type of brain tumor in humans and dogs -- are extremely similar genetically.
Published New system triggers cellular waste disposal
(via sciencedaily.com) Original source Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.
Published Detecting pathogens faster and more accurately by melting DNA
(via sciencedaily.com) Original source A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published 'The future is fungal': New research finds that fungi that live in healthy plants are sensitive to climate change
(via sciencedaily.com) Original source Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
Published Science fiction meets reality: New technique to overcome obstructed views
(via sciencedaily.com) Original source Using a single photograph, researchers created an algorithm that computes highly accurate, full-color three-dimensional reconstructions of areas behind obstacles -- a concept that can not only help prevent car crashes, but help law enforcement experts in hostage situations, search-and-rescue and strategic military efforts.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders
(via sciencedaily.com) Original source Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.