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Categories: Biology: General, Paleontology: Climate

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Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.

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Using optogenetics, researchers have detected a new acid sensor in plant cells that is addressing a cell-internal calcium store.  

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A new analysis sheds light on the ancestry and genetics of woolly dogs, a now extinct breed of dog that was a fixture of Indigenous Coast Salish communities in the Pacific Northwest for millennia. Anthropologists and biologists analyzed genetic clues preserved in the pelt of 'Mutton,' the only known woolly dog fleece in the world, to pinpoint the genes responsible for their highly sought-after woolly fur. The study's findings include interviews contributed by several Coast Salish co-authors, including Elders, Knowledge Keepers and Master Weavers, who provided crucial context about the role woolly dogs played in Coast Salish society.

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An international team of scientists led by geneticists and disease biologists has used ancient DNA to trace the evolution of Marek's Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year. The findings show how viruses evolve to become more virulent and could lead to the development of better ways to treat viral infections.

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New study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms. However, this protective effect is lost when only single species of gut bacteria are present. The researchers found that protective communities block the growth of harmful pathogens by consuming nutrients that the pathogen needs.

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An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study. The study findings draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called 'long-term non-progressors' or 'elite controllers' (LTNPs/ECs).

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Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.   

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In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.  

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A new study of the remains of prehistoric and modern African antelopes found that AI technology accurately identified animals more than 90% of the time compared to humans, who had much lower accuracy rates depending on the expert.

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New research has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children's underdeveloped gut microbiomes. The study also has identified the important bacterial strains that process these biochemical components. The findings may help guide treatment with a current food formulation and enable creation of new, more effective formulations in the future.

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Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.

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The high-altitude hero of the Himalayas, yak are among the few large animals that can survive the extremely cold, harsh and oxygen-poor conditions of the Tibetan Plateau. In the mountainous regions of Asia, yak and yak-cattle hybrids serve as vital sources of meat, milk, transportation and fuel. However, little is known about their history: when or where yak were domesticated. In a new study, researchers report archaeologically and genetically confirmed evidence for domestic yak, dating back 2,500 years, by far the oldest record.  

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This holiday season brings surprising news about your Christmas tree. Scientists just discovered that globally, trees growing in wetter regions are more sensitive to drought. That means if your tree hails from a more humid clime, it's likely been spoiled for generations.

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Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.

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Researchers have shown that the effects of wildfires are not limited to terrestrial ecosystems. Aquatic ecosystems are also undergoing rapid changes. The study found that fire debris transforms lakes and other aquatic ecosystems, with implications for fisheries and water quality.

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Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.

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A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.

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Plants emit odors for a variety of reasons, such as to communicate with each other, to deter herbivores or to respond to changing environmental conditions. An interdisciplinary team of researchers carried out a study to investigate how biodiversity influences the emission of these substances. For the first time, they were able to show that species-rich forests emit less of these gases into the atmosphere than monocultures. It was previously assumed that species-rich forests release more emissions. The Leipzig team has now been able to disprove this assumption experimentally.

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A new study finds that precipitation levels during nesting season are not related to reproductive success for wild turkeys, which runs counter to the conventional wisdom regarding the role that rainfall plays in wild turkey nesting success. The findings shed new light on how climate change may affect wild turkey populations.

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A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.