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Categories: Biology: General, Mathematics: Puzzles

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The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis. Now, an article challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice.

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A rare subtype of the world's most common parasite, Blastocystis, has been found to produce a unique by-product of its metabolism, which can cause gut inflammation under normal gut conditions.

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Recent study sheds new light on the enigmatic early evolution of snakes by examining an unexpected source: their brains. The results emphasize the significance of studying both the soft parts of animals’ bodies and their bones for understanding how animals evolved.

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The rapid formation of 500 different species of fish in a single lake, each with specialized ecological roles, resulted from a small but genetically diverse hybrid population.

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Recent discoveries in the field of epigenetics, the study of inheritance of traits that occur without changing the DNA sequence, have shown that chronological age in mammals correlates with epigenetic changes that accumulate during the lifetime of an individual. In humans, this observation has led to the development of epigenetic clocks, which are now extensively used as biomarkers of aging. While these clocks work accurately from birth until death, they are set back to zero in each new generation. Now, an international team shows that epigenetic clocks not only exist in plants, but that these clocks keep ticking accurately over many generations.

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Researchers have zeroed in on C. auris' uncanny ability to stick to everything from skin to catheters and made a startling discovery: it uses a protein similar to that used by barnacles and mollusks.

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Scientists have identified the source of antibiotic resistance that emerged within bacteria driving the ongoing Yemen cholera epidemic.

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Surprising findings on the development of sea anemones suggest that a predatory lifestyle molded their evolution and had a significant impact on the origin of their nervous system. The researchers were able to show that the young life stages (larvae) of the small sea anemone Aiptasia actively feed on living prey and are not dependent on algae. To capture its prey, the anemone larvae use specialized stinging cells and a simple neuronal network.

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The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

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Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa. Scientists have detected the emergence and spread in Eritrea of parasites with both artemisinin resistance and genome modifications that prevent their detection with rapid diagnostic tests, thereby jeopardizing malaria control and elimination campaigns in the region and potentially elsewhere in Africa.

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A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.

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Some substances in medicines, household items and the environment are known to affect prenatal child development. Researchers tested the effects of five drugs (including caffeine and the blood thinner warfarin) on the growth of zebrafish embryos. They found that all five had the same effect, impairing the migration of bone-forming cells which resulted in the onset of facial malformation. Zebrafish embryos grow quickly, are transparent and develop outside of the parent's body, making them ideal for studying early development. A zebrafish-based system could be used to easily screen for potentially harmful substances, reducing animal testing on mammals and supporting parents-to-be when making choices for themselves and their baby.

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Paleontologists discover possible DNA remains in fossil turtle that lived 6 million years ago in Panama, where continents collide.

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Humanity continuously emits greenhouse gases and thereby worsens global warming. Increasing research efforts go into developing strategies to convert these gases, such as carbon dioxide (CO2), into valuable products. CO2 accumulates dramatically over the years and is chemically very stable, thus challenging to transform. Yet, for billions of years, some microbes have actively captured CO2 using highly efficient enzymes. Scientists have now isolated one of these enzymes. When the enzyme was electronically branched on an electrode, they observed the conversion of CO2 to formate with perfect efficiency. This phenomenon will inspire new CO2-fixation systems because of its remarkable directionality and rates.

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Three recessive genes are required to give carrots their orange color -- and the beneficial precursor of vitamin A.

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Brain circuits for vision develop without any kind of input from the retina in zebrafish.

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For decades, fish-eating killer whales in the Pacific Northwest have been observed harassing and even killing porpoises without consuming them —- a perplexing behavior that has long intrigued scientists.

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A new article has analyzed another understudied behavior in baleen (filter-feeding) whales such as humpback whales in different populations across the northern and southern hemispheres. They appeared to roll around and 'play' with clumps of kelp and seaweed at the water's surface. The research also emphasizes that the behavior was similar in different individuals, regardless of where in the world it occurred.

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A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development.

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Past cycles of climate change, along with human exploitation, have led to only small and isolated stocks of Atlantic walrus remaining. The current population is at high risk of the same issues affecting them severely, according to a new study.