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Categories: Biology: Microbiology, Space: Structures and Features

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Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.

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A new study analyzing wastewater samples from several aged care facilities and retirement homes, has uncovered worrying signs of antimicrobial resistance (AMR), a concerning trend in aged care facilities.

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To produce plant-based cheeses that feel and taste like dairy cheese, scientists have their sights set on fermentation. In a new research result, scientists demonstrate the potential of fermentation for producing climate-friendly cheeses that people want to eat.

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Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.

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A new study into sepsis in neonatal babies has uncovered the secrets of the bacteria’s success in causing this life-threatening condition. Using genomic sequencing, they have found how certain strains of bacteria that usually live harmlessly on the skin can evade control measures by colonizing babies’ guts. This will provide new ways to control this threat to babies’ health.

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In a breakthrough for environmentally friendly chemical production, researchers have developed an economical way to make succinic acid, an important industrial chemical, from sugarcane. The team has created a cost-effective, end-to-end pipeline for this valuable organic acid by engineering a tough, acid-tolerant yeast as the fermenting agent, avoiding costly steps in downstream processing. Succinic acid is a widely used additive for food and beverages and has diverse applications in agricultural and pharmaceutical products. This same pipeline can be used to produce other industrially important organic acids from crops rather than petroleum-based processes, significantly reducing greenhouse gas emissions.

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In the James Webb Space Telescope’s (JWST) first images of the universe’s earliest galaxies, the young galaxies appear too bright, too massive and too mature to have formed so soon after the Big Bang. Using new simulations, a team of astrophysicists now has discovered that these galaxies likely are not so massive after all. Although a galaxy’s brightness is typically determined by its mass, the new findings suggest that less massive galaxies can glow just as brightly from irregular, brilliant bursts of star formation.

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Gut microbes found in wild wolves may be the key to alleviating a debilitating gastrointestinal condition common to domestic dogs.

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Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.

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Scientists have characterized the genome of a metal-loving bacteria with an affinity for rare earth elements. The research paves the way towards replacing the harsh chemical processing of these elements with a benign practice called biosorption.

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Viruses in soil may not be as destructive to bacteria as once thought and could instead act like lawnmowers, culling older cells and giving space for new growth, according to research.

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An evolutionary gateway which helps pneumonia cells become resistant to antibiotics has been discovered.

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Altered measles and mumps viruses could be used as a platform to create a trivalent COVID-19 vaccine that triggers immunity to multiple variant strains of the SARS-CoV-2 virus, new research in animals suggests.

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Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.

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In recent years, astronomy has seen itself in a bit of crisis: Although we know that the Universe expands, and although we know approximately how fast, the two primary ways to measure this expansion do not agree. Now astrophysicists suggest a novel method which may help resolve this tension.

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Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.

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Researchers have developed an improved way to test potential vaccines against bird flu.

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A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but at one-third the size of the Cas9 enzyme commonly used for gene editing. The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.

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The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis. Now, an article challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice.

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Up to 15 percent of children and five percent of adults are affected by the chronic inflammatory skin disease atopic dermatitis. Despite advanced therapy measures, the severe itching and eczema, especially on the elbows or knees, cause great distress to the patients. Medical researchers have now discovered a new approach: bacteriophages, which colonize the skin as viral components of the microbiome and can drive the development of innovative atopic dermatitis therapies.