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Categories: Chemistry: Organic Chemistry
Published Water splitting reaction for green hydrogen gas production improved
(via sciencedaily.com) Original source Electrochemical catalysts used in water splitting often show poor performance due to low electrical conductance of (oxy)hydroxide species produced in situ. To overcome this challenge, researchers have now designed an electrode with Schottky Junction formed at the interface of metallic Ni-W5N4 and semiconducting NiFeOOH. The proposed electrode shows excellent catalytic activity and can facilitate industrial seawater splitting continuously for 10 days.
Published AI programs spat out known data and hardly learned specific chemical interactions when predicting drug potency
(via sciencedaily.com) Original source Artificial intelligence (AI) is on the rise. Until now, AI applications generally have 'black box' character: How AI arrives at its results remains hidden. A cheminformatics scientist has now developed a method that reveals how certain AI applications work in pharmaceutical research. The results are unexpected: the AI programs largely remembered known data and hardly learned specific chemical interactions when predicting drug potency.
Published Solar-powered device produces clean water and clean fuel at the same time
(via sciencedaily.com) Original source A floating, solar-powered device that can turn contaminated water or seawater into clean hydrogen fuel and purified water, anywhere in the world, has been developed by researchers.
Published How to use AI for discovery -- without leading science astray
(via sciencedaily.com) Original source In the same way that chatbots sometimes 'hallucinate,' or make things up, machine learning models designed for scientific applications can sometimes present misleading or downright false results. Researchers now present a new statistical technique for safely using AI predictions to test scientific hypotheses.
Published Chemists image basic blocks of synthetic polymers
(via sciencedaily.com) Original source Researchers have developed a new method to image polymerization catalysis reactions one monomer at a time.
Published Scientists use quantum biology, AI to sharpen genome editing tool
(via sciencedaily.com) Original source Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
Published Liquid metals shake up century-old chemical engineering processes
(via sciencedaily.com) Original source Liquid metals could be the long-awaited solution to 'greening' the chemical industry, according to researchers who tested a new technique they hope can replace energy-intensive chemical engineering processes harking back to the early 20th century.
Published Photo battery achieves competitive voltage
(via sciencedaily.com) Original source Researchers have developed a monolithically integrated photo battery using organic materials. The photo battery achieves an unprecedented high discharge potential of 3.6 volts. The system is capable of powering miniature devices.
Published Charged 'molecular beasts' the basis for new compounds
(via sciencedaily.com) Original source Mass spectrometers are high-tech machines that play an important role in our society. They are highly sensitive analytical instruments that are indispensable in areas such as medical diagnostics, food quality control and the detection of hazardous chemical substances. A research group is working to modify mass spectrometers so that they can be used for a completely different purpose: the chemical synthesis of new molecules.
Published Self-powered microbial fuel cell biosensor for monitoring organic freshwater pollution
(via sciencedaily.com) Original source Biodegradable waste from plant and animal sources released into freshwater ecosystems is a significant environmental concern. Nonetheless, current methods for assessing water quality seem more or less impractical due to their complexity and high costs. In a promising development, a team of researchers has successfully constructed a self-sustaining and buoyant biosensor using inexpensive carbon-based materials for monitoring water quality at the inlets of freshwater lakes and rivers.
Published Chemists make breakthrough in drug discovery chemistry
(via sciencedaily.com) Original source Chemists offer two new methods to develop a way to easily replace a carbon atom with a nitrogen atom in a molecule. The findings could make it easier to develop new drugs.
Published Breakthrough discovery sheds light on heart and muscle health
(via sciencedaily.com) Original source The human heart, often described as the body's engine, is a remarkable organ that tirelessly beats to keep us alive. At the core of this vital organ, intricate processes occur when it contracts, where thick and thin protein-filaments interact within the sarcomere, the fundamental building block of both skeletal and heart muscle cells. Any alterations in thick filament proteins can have severe consequences for our health, leading to conditions such as hypertrophic cardiomyopathy and various other heart and muscle diseases.
Published New Nijmegen method reveals hidden genetic variations
(via sciencedaily.com) Original source Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published Efficient biohybrid batteries
(via sciencedaily.com) Original source Formic acid, which can be produced electrochemically from carbon dioxide, is a promising energy carrier. A research team has now developed a fast-charging hybrid battery system that combines the electrochemical generation of formic acid as an energy carrier with a microbial fuel cell. This novel, fast-charging biohybrid battery system can be used to monitor the toxicity of drinking water, just one of many potential future applications.
Published New frequency comb can identify molecules in 20-nanosecond snapshots
(via sciencedaily.com) Original source Researchers have developed a device that can detect the presence of specific molecules in a sample every 20 nanoseconds, or billionths of a second. With this new capability, researchers can potentially use frequency combs to better understand the split-second intermediate steps in fast-moving processes ranging from the workings of hypersonic jet engines to the chemical reactions between enzymes that regulate cell growth.
Published 'Plug and play' nanoparticles could make it easier to tackle various biological targets
(via sciencedaily.com) Original source Engineers have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins. The surface of the nanoparticles is engineered to host any biological molecules of choice, making it possible to tailor the nanoparticles for a wide array of applications, ranging from targeted drug delivery to neutralizing biological agents.
Published How to protect biocatalysts from oxygen
(via sciencedaily.com) Original source There are high hopes for hydrogen as the key to the energy transition. A specific enzyme group found in algae and in bacteria can produce molecular hydrogen simply by catalyzing protons and electrons. However, the enzyme group is so sensitive to oxygen that commercial use of the hydrogen produced by this process as a green energy source is not yet possible. Researchers have now increased the oxygen stability of a hydrogen-producing enzyme by genetically generated channel blockages.
Published Cat-ching criminals with DNA from pet hairs
(via sciencedaily.com) Original source Cat hair could be the purr-fect way to catch criminals, according to researchers.
Published DNA Origami nanoturbine sets new horizon for nanomotors
(via sciencedaily.com) Original source Researchers introduce a pioneering breakthrough in the world of nanomotors -- the DNA origami nanoturbine. This nanoscale device could represent a paradigm shift, harnessing power from ion gradients or electrical potential across a solid-state nanopore to drive the turbine into mechanical rotations. The core of this pioneering discovery is the design, construction, and driven motion of a 'DNA origami' turbine, which features three chiral blades, all within a minuscule 25-nanometer frame, operating in a solid-state nanopore. By ingeniously designing two chiral turbines, researchers now have the capability to dictate the direction of rotation, clockwise or anticlockwise.
Published Researchers develop DANGER analysis tool for the safer design of gene editing
(via sciencedaily.com) Original source A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the CRISPR technology for genome editing. However, there are some challenges in the use of CRISPR. The new analysis system overcomes these challenges and allows researchers to perform safer on- and off-target assessments without a reference genome. It holds the potential for applications in medicine, agriculture, and biological research.